1. Project Overview Jörg Freund, Siemens David Manset, MaatGKnowledge HG09, 29-Jun-09, Berlin

2. 2Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Health-e-Child at a Glance Establish multi-site, vertical, and longitudinal integration of data, information and knowledge Develop a GRID based platform, supported by robust search, optimisation and matching Build enabling tools and services that improve patient care Two main use case scenarios “Aiding the Clinician in Decision Making” “Clinical Studies” Healthy Child Decision Support Systems Integrated Disease Modeling Knowledge Discovery Augment Guidance Guidance Enrich Real-time alert On-line learning Observation Process Sensors Imaging Genomics Lab Data Proteomics Demographics Physician Notes Life Style Time Organ Tissue Cell Molecule Population Individual Vertical Data Integration Integrated Medical Database

3. 3Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Health-e-Child Platform Overview Gateway Grid Grid – EGEE gLite IGGGOSH NECKEROPBG Ontological Layer Query Processing Data Management Cardiology Right Ventricular Overload CardiomyopathyCardiology Right Ventricular Overload CardiomyopathyRheumatology Juvenile Idiopathic ArthritisRheumatology NeuroOncology Brain Tumors / GliomasNeuroOncology Knowledge Discovery Decision Support Systems Disease Models

4. 4Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin 4 paediatric hospitals  4 paediatric hospitals  IGG - Gaslini, Genoa, Italy  GOSH, London, UK  NECKER, Paris, France  OPBG, Rome, Italy  Strong interdisciplinary team  Strong interdisciplinary team across  Countries and languages  Technical and clinical fields  Research on three paediatric areas  Arthritis  Cardiac Disorders  Brain Tumours Health-e-Child Network Year 3 7 technical 7 technical sites 4 clinical 4 clinical sites (1 currently under deployment finalisation)

5. 5Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Overview ICDGALDALMQPE CardiologyCardiologyRheumatologyRheumatologyNeuroOncologyNeuroOncology Auth3D Browser MDMan Heatmap Pat. Browser Data Acq CaseReasoner AITION Treemaps SOFA JIAnnotate CardioViz3D 3DRegTool RADBuilder Automator GridOS

6. 6Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Virtual Physiological Child Decision Support

7. 7Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Knowledge Discovery Virtual Physiological Children

8. 8Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Pediatrics Knowledge Applications

9. 9Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Demonstration Health-e-Child Demonstrator Integrated Demonstrator Domains Cardiology Rheumatology Oncology Sites Gaslini, Italy Necker, France GOSH, UK Scenarios Personalized Decision support Similarity Search Knowledge Discovery IT Innovation Machine Learning Imaging Data Integration Grid... + + +

10. 10Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin @neurIST Collaboration with @neurIST (3DKnowl. + @neuLINK) @neurIST Collaboration with @neurIST (3DKnowl. + @neuLINK) External Collaborations Network US Network and Collaboration expansion to the US

11. 11Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin

12. 12Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin EuroNews TV documentary http://www.euronews.net/2009/06/17/ new-frontiers-of-imaging-the-human-body/http://www.euronews.net/2009/06/17/ new-frontiers-of-imaging-the-human-body/