1. 11 11/16/2015 Filo Viruses Hugh B. Fackrell fackrel@Uwindsor.ca Filename: Filovir.ppt

2. 22 11/16/2015 Filoviruses Outline l Structure l Classification l Multiplication l Clinical manifestations l Epidemiology l Diagnosis l Control Baron’s Web Site

3. 33 11/16/2015

4. 44 Ebola virus First photograph 1976

5. 55 11/16/2015

6. 66 Ebola virus

7. 77 11/16/2015 Ebola virus growing in cell

8. 88 11/16/2015 Marburg Virus

9. 99 11/16/2015 Filovirus l cause disease in humans due to contact with monkeys. l.......................Ebola virus.......................... l Book “The Hot Zone” l Movie “Outbreak” l First recognized in 1976 - Zaire, Kenya, l..............Zimbabwe 18% have antibodies CDC Fact sheet

10. 10 11/16/2015 Filovirus l Ebola virus l Fever, hemorrhages from multiple sites, diarrhea,vomiting, myalgia, pharyngitis, conjunctivitis, rash. l Patient with all symptoms. 90% death rate l Marburg virus l Lab workers exposed to monkey tissue.7/25 died. l Symptoms same as Ebola. The natural reservoir not identified l Clinical note: pg. 656 Jensen & Wright

11. 11 11/16/2015 DONE!!!