1. The Mind’s Eye: Imaging Structure and Function in the Living Brain Daniel K. Sodickson, MD, PhD Vice-Chair for Research, Department of Radiology Director, Center for Biomedical Imaging October 21, 2009

2. DK Sodickson 10/09 The Mind’s Eye: Imaging Structure and Function in the Living Brain Yulin Ge, MD Pathology slide (invasive) MRI (noninvasive)

3. 420 tons steel Big Magnet: 7 Tesla 140,000 x earth’s field State-of-the-art electronics Leading-edge arrays of transmitters and detectors BIGAPPLE 70 staff 20 principal investigators 4 onsite industry representatives 1 apple High-field MRI @ NYU

4. Residual vascular tumor Multiple Sclerosis Residual vascular tumor Cancer Alzheimer’s Disease ADHD Brain Injury Training Learning Wisdom The field of radiology is undergoing a remarkable trans- formation. Once limited to the study of anatomy, radiolo- gists can now visualize the function of tissue, taking the art and science of diagnosis to unprecedented levels.  - Robert I. Grossman, MD Residual vascular tumor

5. DK Sodickson 10/09 Imaging Structure and Function in the Living Brain: Outcomes Characterize the brain at work Catch disease early –Alzheimer’s, ADHD, brain cancer, MS, brain injury, stroke … Guide treatment and evaluate new drugs Generate new scientific understandings See the unseen Clinical needs, technological solutions