Presentation is loading. Please wait.

Presentation is loading. Please wait.

Supporting Vascular Risk Assessment: QDScore www.qdscore.org www.qdscore.org Julia Hippisley-Cox 15 th April 2010.

Published byDamon Powers Modified over 9 years ago

Similar presentations

Presentation on theme: "Supporting Vascular Risk Assessment: QDScore www.qdscore.org www.qdscore.org Julia Hippisley-Cox 15 th April 2010."— Presentation transcript:

1 Supporting Vascular Risk Assessment: QDScore www.qdscore.org www.qdscore.org Julia Hippisley-Cox 15 th April 2010

2 04Feb2009 QRisk © 2008 All rights reserved Background Diabetes major causes of morbidity and mortality Many risk factors overlap with CVD Interventions may prevent upto 2/3 cases Early diagnosis improves outcomes Evidence that intervention is cost-effective Existing evidence of health inequalities Previous scores limited by size and samples

3 QRisk © 2008 All rights reserved Methodology QDScore Similar to QRISK2 E&W Cohort analysis based QResearch First diagnosis of type 2 diabetes 15 year study period 1993 to 2008 2.5m patients aged 25-79 78,000 new cases Type 2 diabetes Largest ever such study worldwide

4 QRisk © 2008 All rights reserved Risk Factors in Diabetes Score (suitable for patient self assessment) Age & Sex Deprivation & Self Assigned Ethnicity Body Mass Index Smoking Status Family history of diabetes Treated Hypertension Corticosteroids* Cardiovascular Disease

5 QRisk © 2008 All rights reserved Self Assigned Ethnicity Initial analysis NHS 16+1 categories Categories used for analysis White Indian Pakistani Bangladeshi Other Asian Black Caribbean Black African Chinese Other

6 04Feb2009 QRisk © 2008 All rights reserved Comparison with CRS Compared performance with Cambridge Risk Score (CRS) CRS has similar variables but doesn’t have Ethnicity Deprivation CVD Also CRS not based on cohort

7 04Feb2009 QRisk © 2008 All rights reserved Validation 0ne third sample of QR database (independent practices) Similar statistical tests to previous study Independent external validation by Oxford (in press)

8 04Feb2009 QRisk © 2008 All rights reserved Age-standardised Incidence of Diabetes by Ethnicity per 1000

9 04Feb2009 QRisk © 2008 All rights reserved Age standardised prevalence risk factors in men

10 04Feb2009 QRisk © 2008 All rights reserved Risk Ratios for Diabetes

11 How might we use this? No existing threshold for screening If we risk score the entire population and take top 10% We will capture half of all the new cases of diabetes in the next 10 years If we take top 20% then we will capture 70% of new cases. 22 nd May 2008 QRisk © 2008 All rights reserved

12 Summary QDSCore 1 st score to predict 10 yr risk diabetes incl ethnicity & deprivation But no need for lab tests Better performance than existing scores Can be applied to whole population Can be used at the point of care Can be used for self assessment 04Feb2009 QRisk © 2008 All rights reserved

Download ppt "Supporting Vascular Risk Assessment: QDScore www.qdscore.org www.qdscore.org Julia Hippisley-Cox 15 th April 2010."

Similar presentations

The Health Survey for England 2004 Margaret Blake (National Centre for Social Research)

The Health Survey for England 2004 Margaret Blake (National Centre for Social Research)
Dr S Saxena 1 Dr G Ambler 2 Prof. TJ Cole 3 Prof A. Majeed 1 1 Imperial College London, 2 UCLH Trust, 3 Institute of Child Health.

Dr S Saxena 1 Dr G Ambler 2 Prof. TJ Cole 3 Prof A. Majeed 1 1 Imperial College London, 2 UCLH Trust, 3 Institute of Child Health.
What we know about Health in BME Communities Dr. Sakthi Karunanithi Lancashire County Council.

What we know about Health in BME Communities Dr. Sakthi Karunanithi Lancashire County Council.
Associations between Obesity and Depression by Race/Ethnicity and Education among Women: Results from the National Health and Nutrition Examination Survey,

Associations between Obesity and Depression by Race/Ethnicity and Education among Women: Results from the National Health and Nutrition Examination Survey,
Is low-dose Aspirin use associated with a reduced risk of colorectal cancer ? a QResearch primary care database analysis Prof Richard Logan, Dr Yana Vinogradova,

Is low-dose Aspirin use associated with a reduced risk of colorectal cancer ? a QResearch primary care database analysis Prof Richard Logan, Dr Yana Vinogradova,
COHORH STUDY A research paper on BMJ. What is cohort study? Investigates from exposure to outcome, in a group of patients without, or with appropriate.

COHORH STUDY A research paper on BMJ. What is cohort study? Investigates from exposure to outcome, in a group of patients without, or with appropriate.
Advances and Controversies in Cardiovascular Risk Prediction Peter Brindle General Practitioner R&D lead Bristol, N.Somerset and S.Glouc PCTs Promises,

Advances and Controversies in Cardiovascular Risk Prediction Peter Brindle General Practitioner R&D lead Bristol, N.Somerset and S.Glouc PCTs Promises,
Www.alcoholandhealth.org1 Journal Club Alcohol and Health: Current Evidence July–August 2004.

Journal Club Alcohol and Health: Current Evidence July–August 2004.
Healthy People 2010 Focus Area 12: Heart Disease and Stroke

Healthy People 2010 Focus Area 12: Heart Disease and Stroke
Exposure to bisphosphonates and risk of non-gastrointestinal cancers: nested case-control studies SAPC 2013, Nottingham Yana Vinogradova, Carol Coupland,

Exposure to bisphosphonates and risk of non-gastrointestinal cancers: nested case-control studies SAPC 2013, Nottingham Yana Vinogradova, Carol Coupland,
+ Towards personalised medicine – assessing risks and benefits for individual patients Prof Julia Hippisley-Cox, University of Nottingham, Tony Mitchell.

+ Towards personalised medicine – assessing risks and benefits for individual patients Prof Julia Hippisley-Cox, University of Nottingham, Tony Mitchell.
Chronic kidney disease Mr James Hollinshead Public Health Analyst East Midlands Public Health Observatory (EMPHO) UK Renal Registry 2011 Annual Audit Meeting.

Chronic kidney disease Mr James Hollinshead Public Health Analyst East Midlands Public Health Observatory (EMPHO) UK Renal Registry 2011 Annual Audit Meeting.
Professor Julia Hippisley-Cox University of Nottingham.

Professor Julia Hippisley-Cox University of Nottingham.
Using the Health Survey for England to examine ethnic differences in obesity, diet and physical activity Vanessa Higgins & Angela Dale Centre for Census.

Using the Health Survey for England to examine ethnic differences in obesity, diet and physical activity Vanessa Higgins & Angela Dale Centre for Census.
1 www.ncl.nhs.uk ANNUAL PUBLIC HEALTH REPORT 2011 Extending life in Islington Harriet Murrell Public Health Strategist. on behalf of Islington’s Public.

1 ANNUAL PUBLIC HEALTH REPORT 2011 Extending life in Islington Harriet Murrell Public Health Strategist. on behalf of Islington’s Public.
Cardiovascular Disease in Women Module I: Epidemiology.

Cardiovascular Disease in Women Module I: Epidemiology.
Health priorities for Charnwood, 2010 and beyond Dr Mike McHugh Consultant in Public Health NHS Leicestershire County and Rutland 7/9/10.

Health priorities for Charnwood, 2010 and beyond Dr Mike McHugh Consultant in Public Health NHS Leicestershire County and Rutland 7/9/10.
Chiu et al., CMAJ 2010 Do ethnic groups living in Ontario differ in their cardiovascular risk profiles? Maria Chiu, MSc, PhD Candidate Inst. of Medical.

Chiu et al., CMAJ 2010 Do ethnic groups living in Ontario differ in their cardiovascular risk profiles? Maria Chiu, MSc, PhD Candidate Inst. of Medical.
SOCIO-ECONOMIC STATUS AND MORTALITY FROM CARDIOVASCULAR DISEASE AMONG PEOPLE WITH TYPE 2 DIABETES IN SCOTLAND (2001-2007) Caroline Jackson, Jeremy Walker,

SOCIO-ECONOMIC STATUS AND MORTALITY FROM CARDIOVASCULAR DISEASE AMONG PEOPLE WITH TYPE 2 DIABETES IN SCOTLAND ( ) Caroline Jackson, Jeremy Walker,
Risk of colorectal cancer in patients taking statins and NSAIDS Dr Yana Vinogradova, Prof Julia Hippisley-Cox, Dr Carol Coupland and Prof Richard Logan.

Risk of colorectal cancer in patients taking statins and NSAIDS Dr Yana Vinogradova, Prof Julia Hippisley-Cox, Dr Carol Coupland and Prof Richard Logan.

Similar presentations

Ads by Google