1. Hemophilia By: Britta Roe & Natalie Hayne

2. Why We Chose It ●We chose to study the non-communicable disease hemophilia because it is relatively unheard of, fairly uncommon, and mentioned throughout history.

3. Basic Information Hemophilia is a genetic disorder. It is carried in the X chromosome, so it affects almost entirely men, although women can be carries, and are in rare cases affected. The disease prevents blood clots from forming when the sufferer is cut or bruised.

4. History Often referred to as ‘the Royal Disease’. Initially, it was treated with Aspirin, which actually worsened the disease. Queen Victoria of Spain passed the disease along to all of her children, two of whom died of internal bleeding before the age of 30.

5. Cause Hemophilia is genetically inherited; passed on from mother to child (usually mother to son) This causes a deficiency in several clotting proteins found in the platelet portion of the blood Blood contains 4 parts; Plasma, platelets, red blood cells and white blood cells

7. Signs and Symptoms Spontaneous internal and external bleeding Bleeding for prolonged periods of time Frequent bruising Bleeding of joints

8. Cure/Treatment There is no cure Liver transplants may lessen the disease, but in some cases, they create alternative problems. Both medicines and gene therapy are available for short term relief to stop bleeding

9. Long Term Effects Deep internal bleeding Joint damage Arthritis Hemorrhage

10. Prevention There is no way of preventing hemophilia.

11. Quiz Question #1 Is hemophilia more common in boys or girls? a. Boysb. Girls c. They are equally d. No one common

12. Quiz Question #2 Which chromosome is hemophilia passed along by? a. XY Chromosomes b. Y Chromosome c. X Chromosome d. Z Chromosome

13. Quiz Question #3 Which queen passed along hemophilia to her sons, who later died from the disease? a. Queen Elizabeth IIb. Queen Victoria c. Queen Mary Vd. King Henry VIII