1. Cell Cycle and Cell Division

2. BIG PICTURE

3. Mitosis 2n 2n 2n One (Diploid) Cell becomes Two (Diploid) Cells
Example : Cats
Somatic Cells have 38 (2n) chromosomes
Sex cells have 19 (n) chromosomes

4. Chromosomes Contain the genetic information
How this information is transmitted from one cell to another
2 sister chromatids
DNA Replication
Centromere
Arm
Genes/DNA
Chromosome
(unduplicated)
Chromosome
(duplicated)

5. A Chromosome

6. Number of Chromosomes Types of Chromosomes (Humans)
Body (Autosomes) – 44 chromosomes (22 pairs)
Sex – 2 chromosomes (1 pair)
(females XX, males XY)
Total Number of Chromosomes = 46

7. To Begin - Terminology Somatic cell – A body cell (muscle, skin, etc)
Cytokinesis
– the cytoplasm of one cell is divided evenly into the two daughter cells
Sister Chromatids

8. The End Result
Two cells are created with the same genetic information and number of chromosomes as their parent cell.
- *

9. Where does Mitosis occur?
Only occurs in somatic cells (ex. muscle, skin)
Produces diploid somatic cells
*get students to give more examples*

10. Interphase During Interphase:
Growth -> Duplication of chromosomes -> Growth
Takes in nutrients to build proteins
Duplicates chromosomes within the nucleus to create sister chromatids (joined by the centromere)

11. Homologous Pairs

12. Prophase Individual chromosomes shorten and thicken
Strengthens DNA for Mitosis

13. Metaphase
Sister chromatids line up along the middle of the cell

14. Anaphase
The sister chromatids split to form two individual chromosomes
The two individual chromosomes move to opposite ends of the cell

15. Telophase Chromosomes reach the ends of the cell
Nuclear membrane begins forming
Cytokinesis occurs resulting in two daughter cells each containing all cell organelles and 2n chromosomes
Interphase begins again

16. Telophase

17. Make A Chart
List IPMAT down the left side (below each phase list how to remember it!)
Across the top, put:
Genetic Information
Centrioles
Spindle Fibres
Nuclear membrane
Drawing (place a rough labelled sketch in here)
Describe how each of the cell parts involved are behaving in each stage

18. Cell Cycle 3. Cytokinesis = Division of the cytoplasm Two main phases:
Interphase
3 stages
G1 – rapid growth
S – DNA replication
G2 – prepare for mitosis
2. Mitosis (M) = division of the nucleus
4 stages
Prophase
Metaphase
Anaphase
Telophase
3. Cytokinesis = Division of the cytoplasm

19. Mitosis
Interphase
Cytokinesis
Telophase
Prophase
Anaphase
Metaphase

20. Interphase Growth DNA replication
At the end, all chromosome have two sister chromatids

21. Prophase Chromosome formation DNA condenses Nuclear membrane dissolves
Centrioles move to opposite poles of cell

22. Metaphase Centromere of chromosomes joins to spindle fiber
Chromosomes line up in the middle of the cell

23. Anaphase Centromere doubles
Chromatids separate and are pulled to opposite poles by the spindle fibers

24. Telophase Cytokinesis – separation of cytoplasm;
Nuclear membrane reappears in the two daughter cells
Cytokinesis – separation of cytoplasm;
final stage of cell division

25. Mitosis under the microscope
PROPHASE
TELOPHASE
METAPHASE
ANAPHASE

26. Mitosis Lab –Root Tip
Telophase
Prophase
Anaphase
Metaphase
Interphase

30. Vocabulary
The Cell Cycle Chromosomes Interphase Mitosis Prophase Metaphase Anaphase Telophase Cytokinesis

31. Homework
Page 44
Questions #1 - 7

32. Mitosis On the Table
Using pipe cleaners and your text, recreate the stages of mitosis on your desk with a partner
1 partner tries each phase, and the other partner checks to make sure it’s done correctly
Raise your hand for teacher to check
Then switch roles