1. Enzyme Structure and Function

2. Why do we study molecules in biology?
Review the large molecules of life:
break down into

3. Large molecules in food are broken down into smaller molecules to:
Provide energy to the body
Provide building blocks to make new molecules

4. Enzymes Are specialized proteins that help:
Catalyze (“speed up”) reactions
Break down molecules
Build up new molecules
And can be affected by changes in the enzyme’s environment – their activity or effectiveness

5. Enzymes are specific in how they work!
Substrate
Active Site

6. For the audio-visual learners…
Enzyme video clip from Bozeman Biology
The enzyme song!

7. Enzymes lower the activation energy of a chemical reaction.
Activation energy is the amount of energy it takes for a reaction to “go”

8. Inhibitors can get in the way!
These are molecules that interfere with enzyme function.
Competitive Inhibitors
Non-competitive Inhibitors (“allosteric”)
Can slow the work of enzymes, or stop it altogether.

9. Write your summary paragraph
Enzyme Structure and Function
Write your summary paragraph
3 stamps

10. Your Tasks/Homework Read text excerpts,
A specific enzyme catalyzes each cellular reaction
Enzyme inhibitors block enzyme action and can regulate enzyme activity in a cell
Answer follow-up questions on sheet

11. Respond to these questions in the spaces below.
What does “induced fit” refer to, when talking about enzymes?
Explain how an enzyme speeds up a specific reaction.
What does it mean to be an optimal condition for an enzyme”?
List 2 optimal enzyme conditions for humans.
Compare and contrast cofactors and coenzymes.
Compare and contrast competitive inhibitors and non-competitive inhibitors.
What is the advantage of feedback inhibition to a cell?

12. Label where enzymes are produced

13. Quick Review! From essay, What Happens to the Food You Eat?
Why is saliva an important component of the digestive system?
Explain what happens to food as it passes through the stomach into the small intestine.
Why is chewing food such an important function to digestion?
How are large molecules broken down into smaller ones?

14. You Are What You Eat!