20. Figure 1 Cell 2004 116, 281-297DOI: (10.1016/S0092-8674(04)00045-5)

21. Figure 2 Cell 2004 116, 281-297DOI: (10.1016/S0092-8674(04)00045-5)

22. Figure 3 Cell 2004 116, 281-297DOI: (10.1016/S0092-8674(04)00045-5)

23. Table 1 The role of microRNAs in cancers microRNAsTumorigenesis miR-9Neuroblastoma miR-10bBreast cancer miR-15, miR-15aLeukemia, pituitary adenoma miR-16, miR-16-1Leukemia, pituitary adenoma miR-17-5p, miR-17-92Lung cancer, lymphoma miR-20aLymphoma, lung cancer miR-21Breast cancer, cholangiocarcinoma, head & neck cancer, leukemia, cervical cancer, Pancreatic cancer miR-29, miR-29bLeukemia, cholangiocarcinoma miR-31Colorectal cancer miR-34aPancreatic cancer, Neuroblastoma miR-96Colorectal cancer miR-98Head & neck cancer miR-103Pancreatic cancer miR-107Leukemia, pancreatic cancer miR-125a, miR-125bNeuroblastoma, breast cancer miR-128Glioblastoma miR-133bColorectal cancer miR-135bColorectal cancer miR-143Colon cancer, cervical cancer miR-145Breast cancer, colorectal cancer miR-146Thyroid carcinoma miR-155Breast cancer, leukemia, pancreatic cancer miR-181, miR-181a, miR-181cLeukemia, glioblastoma, thyroid carcinoma miR-183Colorectal cancer miR-184Neuroblastoma miR-196a-2Pancreatic cancer miR-221Glioblastoma, thyroid carcinoma, Pancreatic cancer miR-222Thyroid carcinoma miR-223Leukemia miR-301Pancreatic cancer miR-376Pancreatic cancer let-7, let-7a, let-7a-1, let-7a-3Lung cancer, colon cancer Mol Cancer. 2007; 6: 60. Published online 2007 September 25. doi: 10.1186/1476-4598-6-60. Copyright © 2007 Cho; licensee BioMed Central Ltd.

26. Cell 2013 154, 311-324DOI: (10.1016/j.cell.2013.06.026)

27. Martin D. Jansson, Anders H. Lund MicroRNA and cancer Molecular Oncology, Volume 6, Issue 6, 2012, 590–610

33. Steven M. Johnson, Helge Grosshans, Jaclyn Shingara, Mike Byrom, Rich Jarvis, Angie Cheng, Emmanuel Labouri... RAS Is Regulated by the let-7 MicroRNA Family Cell, Volume 120, Issue 5, 2005, 635 - 647 http://dx.doi.org/10.1016/j.cell.2005.01.014

34. Steven M. Johnson, Helge Grosshans, Jaclyn Shingara, Mike Byrom, Rich Jarvis, Angie Cheng, Emmanuel Labouri... RAS Is Regulated by the let-7 MicroRNA Family Cell, Volume 120, Issue 5, 2005, 635 - 647 http://dx.doi.org/10.1016/j.cell.2005.01.014

35. Let-7g impairs proliferation and enhances cell death. Kumar M S et al. PNAS 2008;105:3903-3908 ©2008 by National Academy of Sciences

36. Let-7g-induced tumors maintain overexpression and target suppression. Kumar M S et al. PNAS 2008;105:3903-3908 ©2008 by National Academy of Sciences

40. miR-26a facilitates gliomagenesis in vivo. Huse J T et al. Genes Dev. 2009;23:1327-1337 ©2009 by Cold Spring Harbor Laboratory Press

41. miR-26a represses PTEN expression in murine gliomas. Huse J T et al. Genes Dev. 2009;23:1327-1337 ©2009 by Cold Spring Harbor Laboratory Press