1. Anaesthesia risk Dr. S. Parthasarathy MD., DA., DNB, MD (Acu), Dip. Diab. DCA, Dip. Software statistics PhD (physio) Mahatma Gandhi medical college and research institute – Puducherry – India

2. Define risk Risk is defined as the probability of an outcome within a population Example aspiration pneumonitis in GA of LSCS

3. Does anaesthesia really do this ?? “It is a fact that to anesthetize a human being, to deprive him of consciousness outright, is to take a considerable step along the road to killing him.” —W.G. Hawkins, 1957

5. Mortality This is not only termed as risk

7. Incidence !!! Ulnar neuropathy Awareness Neurological injury after spinal After blocks Not going into the detail

8. What is it ?? Risk Specific population → Specific hazard → Specific conditions. → Specific outcome → Hazard and risk !! LSCS, loss of airway reflexes aspiration Pneumonia

9. In simple terms Risk = Incidence Rate = Persons with Outcome Population Exposed to Hazard

10. a/a+b

11. Practical terms Any morbidity or mortality within 30 days of surgery and anaesthesia Can be taken as related to surgery and anaesthesia 1 in 2 lakh (mortality ), 1 in 25000(morbidity)

12. Goals 1. to assess the potential risk in performing the desired procedure on a specific patient Emergent – ectopic, head injury Cholecystectomy Mammoplasty 2. identify modifiable risk factors

13. Various factors and their percentage 75% 5% 20%

14. Previously it was like this

15. But now

16. Four broad sources of risk. 1. Technical 2. Anaesthetic 3.Medical illness 4. Surgical

17. Possible ways inquests, case reports, case series, study commissions, registries, cohort studies, Clinical trials, clinical practice guidelines establishment of the multidisciplinary Anesthesia Patient Safety Foundation (emulated in Australia and elsewhere

19. Confidential The Secretary of State is satisfied that the disclosure of documents about individual cases prepared for the Enquiry into Perioperative Deaths would be against the public interest and would undermine the whole basis of a confidential study. The data or information sent to the Confidential Enquiry into Perioperative Deaths is therefore protected from subpoena …

20. ASA 1941 Found risk factors ??

21. ASA 1.Healthy patient without medical problems 2 Mild, well-controlled systemic disease 3 Severe systemic disease (not incapacitating) 4 Severe systemic disease (constant threat to life) 5 Moribund (not expected to live 24 hours regardless of operation) 6 Organ donor

23. John Hopkins risk classification Category 1 Minimally invasive procedure; little or no blood loss. - office setting. Minimal risk Category 2 Minimal to moderately invasive procedure. Blood loss <500 mL. Mild risk Category 3 Moderately to significantly invasive procedure. Blood loss potential 500–1,500 mL. Moderate risk Category 4 Highly invasive procedure. Blood loss >1,500 mL. Major risk Category 5 Highly invasive procedure. Blood loss >1,500 mL. Critical risk. Usual postoperative intensive care unit stay with invasive monitoring

24. On the whole risk

25. Edwards Classification of the Relationship of Anesthesia to Operative Morbidity and Mortality Category Definition I When it is reasonably certain that the event or death was caused by the anesthetic agent or technique of administration or in other ways coming directly within the anesthetist's province II Similar to type I cases, but ones in which there is some element of doubt about whether the agent or technique was entirely responsible for the result III Cases in which the patient's adverse event or death was caused by the anesthetic and the surgical technique IV Events entirely referable to surgical technique

27. Some facts Studies of anesthesia-related risk have found that postanesthesia respiratory depression is the major cause of death and coma totally attributable to anesthesia. anesthesia-related cardiac arrest has found it to be attributable to medication administration, airway management, and technical problems of central venous access. Maternal -- increased use of regional anesthesia has led to improvements in outcome.

28. Risks related to anaesthesia only are diminishing Nomorbid anaesthesia

29. Risk in relation to paediatric anaesthesia Mortality decreased Critical incidents in infants younger than 1 year were four times as common as in older children (8.6% vs. 2.1%) and occurred mainly during the maintenance phase of anesthesia (80.6%). Children with a URI are two to seven times more likely to experience respiratory-related adverse events

32. The key factors in the prevention of patient injury are vigilance, up-to-date knowledge, and adequate monitoring Use of Anesthesia Information Management Systems

33. Summary Definition Specific a/a+b 5, 20, 75 %, -- Goals New settings ASA Hopkins Edward ABCD Information systems

34. Thank you all