1. The Neuromuscular Junction

2. T H E N E U R O M U S C U L A R J U N C T I O N

3. The Death Penalty The Issue: Is the death penalty consistent with the Eighth Amendment's prohibition against the imposition of cruel and unusual punishments sodium thiopental (barbiturate) d-turbocurarine or pancuronium bromide KCl

4. T H E N E U R O M U S C U L A R J U N C T I O N Sleepy of Snow White and the Seven Dwarfs – modeled after a friend of Walt Disney who had MG

5. T H E N E U R O M U S C U L A R J U N C T I O N Thomas Willis, 1672, he published De Anima Brutorum(the Soul of Brutes) included, as one of many clinical studies, a report of a woman who had a long-standing paralysis that affected her limbs and her tongue “She speaks freely and readily enough for a while, but after a long period of speech … she is not able to speak a word and is as mute as a fish… Her voice does not return for one or two hours”

6. T H E N E U R O M U S C U L A R J U N C T I O N Signs and Symptoms Initial symptoms of MG may include difficulty speaking (dysarthria), difficulty swallowing (dysphagia), drooping eyelids (ptosis), and double vision (diplopia). Patients often have nasal-sounding speech and weak neck muscles that give the head a tendency to fall forward or backward. These symptoms occur in about 90% of MG cases, are usually intermittent (i.e., come and go), and may disappear for weeks and then recur Myasthenia Gravis

7. T H E N E U R O M U S C U L A R J U N C T I O N

9. Attorney: This myasthenia gravis-does it affect your memory at all? Witness: Yes. Attorney: And in what ways does it affect your memory? Witness: I forget. Attorney: You forget. Can you give us an example of something that you've forgotten?

10. T H E N E U R O M U S C U L A R J U N C T I O N