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Cardiovascular System
Heart
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Heart Location – Mediastinum Pericardial Sac Pericardial Cavity
Pericardial Fluid Parietal Pericardium
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Heart Wall Epicardium = Visceral Pericardium Myocardium Endocardium
Trabeculae carneae Endocardium
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Heart Chambers Atria (Atrium) Auricles Interatrial septum
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Heart Chambers Ventricles Interventricular septum Coronary sulcus
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Valves Atrioventricular (Tricuspid & Bicuspid) Semilunar
Chordae tendineae Papillary muscles Semilunar Pulmonary Aortic
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Vessels Superior Vena Cava Inferior Vena Cava
Pulmonary Trunk (Arteries) Pulmonary Veins Aorta
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Coronary Circulation Aorta Coronary arteries Myocardium Cardiac veins
Coronary sinus Right atrium
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Cardiac Muscle physiology
Myocardium Automated excitement No graded responses No tetany No anaerobic metabolism
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Cardiac Muscle Striated, Involuntary Intercalated discs
Refractory period prevents tetany Energy ATP – aerobic metabolism Coronary circulation providing O2
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Excitation of cardiac muscle
Depolarization to threshold is spontaneous due to decreased outflow of K+ Sinoatrial node (SA) Depolarizes every .8 sec. At rest Depolarizes due to change in permeability Pacemaker
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Conduction Spread to both atria AV node (.1 sec. Delay)
AV Bundle (Bundle of His) Purkinje = Conduction fibers Myocardial cells of ventricle
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Cardiac Cycle Systole RV = 30 mm Hg LV = 120 mm Hg
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Cardiac Cycle Diastole
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Time for cardiac cycle Entire cycle is .8 sec. Atrial systole .1 sec
Atrial diastole .7 sec Ventricular systole .3 sec Ventricular diastole .5 sec
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Pressure Curves Atrium Ventricle Aortic
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Heart Sounds S1 = AV valves closing S2 = Semilunar valves closing
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CARDIAC OUTPUT CO = HR x SV 5-6 liters/minute
70 beats/minute x 80 mls/beat
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Cardiac Reserve Difference between maximum CO and resting CO
Can increase 700%!!
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Heart Rate Control Sympathetic Stimulation Parasympathetic Stimulation
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Stroke Volume Control SV = End-diastolic volume – End-systolic volume
Length of diastole Venous Return
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Stroke Volume Control End-systolic volume Frank-Starling Law
Sympathetic Nervous System Parasympathetic Nervous System
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Factors influencing Cardiac Function
Cardiac Center in Brainstem Exercise,Temperature Ions (K, Ca, Na) Sex Age
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Electrocardiogram EKG, ECG Leads P wave – atrial depolarization
QRS complex – ventricular depolarization T wave - ventricular repolarization
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