1. 1 Urinary System

2. 2 Functions 1. 1. Excretion 2. 2. Elimination 3. 3. Homeostatic Regulation

3. 3 Urinary System  Kidney regions: 1. Cortex  Direct filtration  cortical nephrons  juxtamedullary nephrons 2. Medulla  Reabsorption, Secretion 3. Pelvis excretion

4. 4 Overview of Urinary System Flow Flow 1. 1. Filtration 2. 2. Reabsorption 3. 3. Secretion

5. 5 Glomerular Filtration Filtration membrane Filtration membrane Net Filtration Pressure: Net Filtration Pressure: Glomerular hydrostatic pressure (HPg) (GBHB) Glomerular hydrostatic pressure (HPg) (GBHB) Colloid osmotic pressure (OPg) (BCOP) Colloid osmotic pressure (OPg) (BCOP) Capsular hydrostatic presure (HPg) (CHP) Capsular hydrostatic presure (HPg) (CHP) Glomerular Filtration Rate (GFR) Glomerular Filtration Rate (GFR)

6. 6 Tubular Reabsorption Molecule Reabsorption: glucose, aa, urea Ion Reabsorption: sodium, potassium, calcium, chloride, bicarbonate, phosphate Water reabsorption: Obligatory Water Reabsorption Processes of reabsorption: Diffusion, Osmosis, Active Transport

7. Transport Maximum 7 The mechanism for the tubular reabsorption of glucose can be likened to a conveyor belt running at constant speed. A, When the concentration of glucose in the filtrate is low, all is reabsorbed. B, When the glucose concentration in the filtrate has reached the transport maximum, all carrier sites for glucose are occupied. If the glucose rises further. C, as in the disease diabetes mellitus, some glucose escapes the carriers and appears in the urine.

8. 8 Tubular Secretion Disposes of unwanted solutes What gets secreted into tubules? You Tube Video about types of Diuretics http://www.youtube.com/watch?NR=1&feature=fvwp&v=FjdJdoZcbyA

9. 9 Maintaining Homeostasis Balances: Water/salt pH Blood pressure