3. Robert Hooke 1665 – Micrographia First to identify structure known as cells in cork Predicted that there are 1,259,712,000 cells in the human body

4. Anton van Leewenhoek 1676 – First to observe live cells 1683 – Discovers bacteria

7. Matthias Schleiden 1838- Suggests that all plants are comprised of multiple cells Also discovered the importance of the nucleus

8. Theodor Schwann 1839 – Suggests that all animals are made of many cells Also coined the term “metabolism”

9. The Cell Theory 1) All living things are made of at least one cell 2) Cells are the basic units of life. 3) Cells may develop as a result of spontaneous generation

10. Rudolf Virchow 1855 – Suggests that cells must come from pre-existing cells

11. The Cell Theory Version 2.0 1) All living things are made of at least one cell 2) Cells are the basic units of life. 3) Cells must develop from pre-existing cells

12. CYTOLOGY

13. Cells By The Numbers 10,000 Trillion Cells per person (avg.) 90%+ are not you Hundreds of different cell types made of 100 million proteins. There are 200,000+ different types of these proteins. We know the exact form of 2% of these proteins Electrical activity of 0.1 volts/nanometer = same as a thunderstorm DNA attacked every 8.4 seconds

15. Cellular Unity & Diversity: How and Why?

16. Lab: Fundamentals of Light Microscopy Purpose: To develop facility with using the compound light microscope and to prepare specimens for viewing Methodology: Light microscopy

18. Watch Your Cords!

19. Part 2: Calculating Magnification Ocular = 10x Objective = 4, 10 or 43x Total Magnification = ocular x objective

20. Part 2: Measuring Field of View

21. Approximating Cell Size To calculate approximate cell size, estimate how many cells lined end to end would cover the diameter of the field of view. Divide the field size by this estimated number of cells = appx. cell size (in um)

22. After centering, adjust light before attempting to focus

25. Part 4: Depth of Field

26. PART 5: Wet Mount Slide