1. WELCOME n WE, SAHARA DIAGNOSTICS, WELCOME YOU TO QBC- MALARIA, FILARIA (BY FLUORESCENT MICROSCOPY) PRESENTATION.

2. SCENARIO OF MALARIA IN ORISSA n MALARIA - STILL A GIANT KILLER IN THIS 21 ST CENTURY OF MEDICAL ADVANCEMENT. n A REAL CAUSE OF SERIOUS CONCERN !!!!!!!! n AS PER TIMES OF INDIA PUBLICATION : –ORISSA STILL TOPS THE LIST OF MALARIA DEATHS IN THE COUNTRY. – MALARIA DEATHS IN 2002 & 03 ARE 465 AND 333 RESPECTIVELY. –NEARLY 45% OF TOTAL DEATHS IN THE COUNTRY, OCCUR IN ORISSA ONLY. –ORISSA ALSO COMPRISES 25% OF THE TOTAL MALARIA CASES IN THE COUNTRY. –IN 2003, THE ENTIRE ORISSA WAS IN GRIP OF DEADLY FALCIPARUM MALARIA WHICH IS ABOUT 85% OF TOTAL MALARIA CASES REPORTED.

3. –OUT OF 4.17 LAKH MALARIA CASES REPORTED, 3.46 LAKH AFFECTED BY P.F –EVEN OUR CHIEF MINISTER ON THE OCCASION OF NATIONAL MALARIA PREVENTION MONTH IN JUNE LAST EXPRESSED SERIOUS CONCERN OVER MALARIA DEATHS IN ORISSA. –C.M FURTHER EMPHASIZED THAT MALARIA STILL NOT CONTROLLED AS PER EXPECTATION IN ORISSA DESPITE THE FACT THAT STATE GOVT. HAS ALREADY SPENT Rs. 14 CRORE OVER A SPAN OF LAST 7 YEARS. –SO, C.M. CALLED FOR IMMEDIATE STEPS TO CONTROL THIS DEADED DISEASE ON TOP PRIORITY. –WORLD BANK SPONSORED ENHANCED MALARIA CONTROL PROJECT BEING IMPLEMENTED ALSO IN MOST OF THE DISTRICTS OF ORISSA

4. SAHARA’S QBC FROM ( B-D ), USA, ONLY ORIGINAL THE MANUFACTURER OF THIS WONDERFUL MACHINE TO CONTROL MALARIA n B-D IS MORE THAN 107 YEARS OLD RESEARCH ORIENTED COMPANY. n KNOWN FOR ITS QUALITY MEDICAL EQUIPMENT & SERVICES WORLD WIDE. n B-D IS THE PATENT HOLDER OF QBC MACHINE. n QBC IS THE REGISTERED TRADEMARK OF B-D, USA. n U.S FDA APPROVAL IS GIVEN TO A SYSTEM WHICH CONFORMS ALL PARAMETERS OF APPLIACTION, RELIABILITY, SAFETY & QUALITY OF THE EQUIPMENT. n NO COMPANY EXCEPT B-D IS AUTHORISED TO USE THE NAME – QBC. n QBC SYSTEM BEING MANUFACTURED BY B-D FOR MORE THAN 10 YEARS.

7. INNOVATIVE COMPONENETS MAKE OPERATION & ADAPTATION SIMPLE

10. HOW QBC SYSTEM WORKS n 55 – 65UL OF BLOOD IS TAKEN IN QBC TUBE PRECOATED INTERNALLY WITH ACRADINE ORANGE STAIN & OTHER REAGENTS. n CLOSURE IS ATTACHED AND A PRECISION FLOAT INSERTED BEFORE SPINNING THIS TUBE AT 12,000 RPM IN THE QBC CENTRIFUGE FOR 5 MINUTES. n COMPONENTS OF BUFFY COAT SEPARATES BASED ON THEIR DENSITIES (WBC AT THE TOP & RBC AT BOTTOM OF THE TUBE).

13. WHY QBC SYSTEM WORKS n KEY TO THE SUCCESS OF THE QBC MALARIA TEST IS CONCENTRATION n ON CENTRIFUGATION, ALL PARASITIZED RED BLOOD CELLS LOCATE VISIBLY IN A PREDICTABLE AREA OF THE QBC TUBE – MAKING DETECTION EASY AND FAST. n PARASITIZED RBC ARE LIGHTER IN DENSITY THAN NORMAL RBC SO THEY CONCENTRATE AT THE TOP OF THE RBC LAYER.

14. n PARASITES CONTAIN DNA WHICH TAKE UP THE ACRIDINE ORANGE STAIN AND APPEAR AS BRIGHT SPECK OF LIGHT AMONG NONFLUORESCING RED BLOOD CELLS. n VIRTUALLY ALL PLASMODIA PRESENT IN 60UL OF BLOOD CAN BE EASILY VISUALISED AS ONE ROTATES THE QBC TUBE UNDER THE PARALENS.

15. HIGH SENSITIVITY n STANDARD 65UL QBC TUBE CONTAINS NEARLY 500 TIMES THE VOLUME INSPECTED IN 100 FIELDS OF A THICK SMEAR. n QBC TEST IS 100 TIMES MORE SENSITIVE FOR LOW LEVEL PARASITIMIA THAN THE THICK SMEAR. n QBC MALARIA TEST CAN IDENTIFY ALL THE DIFFERENT SPECIES AND STAGES OF MALARIA LIKE PV, PF, P.MALARIE & P.OVALE WITH STAGES LIKE TROPHOZOITES, GAMETOCYTES & SCHIZONTS ETC. n QUANTIFICATION OF PARASITEMIAS WITH SEVERITY OF INFECTIONS CAN BE KNOWN. n QUALITATIVE & DIFFERENTIAL DIAGNOSIS.

16. BENEFITS OF QBC TECHNIQUE CRITERIACONVENTIONALQBCBENEFITS QUALITY OF BLOOD 4 – 5UL55 – 65ULMORE BLOOD MORE PARASITES USER TRAINING8 – 16 WEEKONE DAYEASY TO LEARN STAININGREQUIREDPRECOATED TUBES USED EASY, FAST & UNIFORM STAINING PARASITE LOSSUPTO 40 % PARASITE LOST DURING SLIDE PREPARATION NO LOSS OF PARASITEMORE SENSITIVE SENSITIVITY100 PARASITE PER 2UL 1 PARASITE PER 2UL 100 TIMES MORE SENSITIVE CONCENTRATIONPARASITES ARE SPREAD PARASITES ARE CONCENTRATED BY CENTRIFUGATION EASE OF DETECTION READING TIME FOR NEGATIVES 8 – 10 MINUTESLESS THAN 1 MINUTE QUICKER AND FASTER

17. BENEFITS OF QBC MALARIA DETECTION SYSTEM n FASTER AND ACCURATE DETECTION OF MALARIA PARASITE IN CAPILLARY AND VENOUS BLOOD – NO FALSE NEGATIVE CASES. n SPECIES IDENTIFICATION IS EASY, FAST AND ACCURATE. n EARLY DETECTION OF LOW PARASITEMIA & BOARDER LINE CASES.

18. n EASY DETECTION FOR PYREXIA OF UNKNOWN ORIGIN CASES. n MANY LIVES CAN BE SAVED FROM DEADLY P. FALCIPARUM BY TIMELY AND SPECIFIC DIAGNOSIS. n SIDE EFFECTS OF LONG TERM TREATMENT OF ANTI MALARIAL DRUGS CAN BE MINIMISED. n AND FINALLY, IT WILL HELP TO CONTROL THE MENACE OF DEADLY KILLER – MALARIA TO A GREAT EXTENT. n IT ALSO DETECTS MICRO FILARIA.

19. AS PER WORLD BANK NORM ONLY B-D QUALIFIES ALL THE CRITERIAS n B-D HAS DESIGNED QBC AND NOT COPIED. n B-D HAS MORE THAN 15 YEARS EXPERIENCE IN MANUFACTURING QBC. n B-D HAS ISO- 9001, U.S FDA AND CE CERTIFICATES FOR COMPLETE QBC SYSTEM. n QBC SYSTEM USES UV RADIATION WHICH CAN BE HAZARDOUS FOR HUMAN EYES BUT OUR SYSTEM IS 100 % SAFE FOR THE END USERS AS IT IS APPROVED BY U.S FDA.

20. THANK YOU ALL SAHARA DIAGNOSTICS