1. Clinical Centre of Vojvodina, Novi Sad
Neurosurgery Clinic
Clinical Centre of Vojvodina, Novi Sad
Serbia
The value of Frame-based CT guided stereotactic biopsy in the treatment of different brain tumors
M. Karan MD
P. Vulekovic MD PhD
Dj. Jajic MD PhD
T. Cigic Md PhD
V. Papic MD PhD
Dj. Djilvesi MD
B. Jelaca MD

2. Introduction
Frame-based stereotactic brain biopsy is an effective way for acquiring histological diagnosis.
This diagnostic method reach all brain locations
It is appropriate for patients of all ages and medical conditions

3. Aim
To evaluate results of the stereotactic biopsy in tretament of different intracranial lesions in our facility

4. Material and methods
Retrospective research at the Clinical Center of Vojvodina
From January 2009 to December 2012
61 patients with different intracranial lesions
Age ranged from 16 to 81, mean age of 70,15 years
CT guided stereotactic biopsy in the general anesthesia

5. Material and methods Indications
Hystological diagnosis of deep intrinsic lesion
Diffuse, infiltrative or multiple lesions
Hystological diagnosis of intracranial lesion in patients in poor medical condition
Decompression and hystological diagnosis of cystic lesion

6. Material and methods Preoperative preparation: Laboratory tests
Frame placement
CT scan contrast agent
Coordinates
Transffer to the operating theater
Laboratory tests
CT scan
MRI, MRS
Informed consent

7. Material and methods
Standard Lexel stereotactic frame modified by Karl-Dieter Lerch
CL instruments GmbH, Germany

8. Material and methods Patient positioning Partialy hair shaving
14mm Burr hole
Aspiration biopsy 8-10 bits, side-cutting Sedan needle
Frozen section PH analisys
Paraffine embedded specimens
Control CT scan

9. Results Thalamus was the most common location (58%) of lesion.
Diagnostic yield was 100%
There were no transient or permanent neurological deficits after the procedure
Patients were discharged usually on the 4th or 5th postoperative day.

10. Complications
There were no transient or permanent neurological deficits after the procedure
Karnofsky performance index was unchanged in all of our patients

11. Conclusion
Frame-based stereotactic biopsy is safe and reliable procedure in the diagnosis and management of brain lesions