Presentation is loading. Please wait.

Presentation is loading. Please wait.

Metabolic Syndrome By: Dr.AP.Ahmed el-Shaer Dr.Mohamed El-Zayat.

Similar presentations


Presentation on theme: "Metabolic Syndrome By: Dr.AP.Ahmed el-Shaer Dr.Mohamed El-Zayat."— Presentation transcript:

1 Metabolic Syndrome By: Dr.AP.Ahmed el-Shaer Dr.Mohamed El-Zayat

2 Definition :

3 Pathophysiology of Metabolic Syndrome 1-Central (Visceral) Obesity 2-Insulin Resistance 3-Atherogenic Dyslipidemia 4-Hypertension 5-Thrombogenicity 6-Inflammation and Endothelial Dysfunction

4 Systemic Effects of Metabolic Syndrome Diabetes Acute stroke in the elderly. kidney Liver Pregnancy Surgical patient

5 Insulin Resistance

6 Strategies for Metabolic Management -Insulin Resistance and Hyperglycemia: A) Insulin secretagogues Sulfonylureas Nonsulfonylureas (repaglinide and nateglinide) B)Insulin-sensitizing agents Biguanides (metformin) PPAR- ligands (thiazolidinediones) -Atherogenic Dyslipidemia: HMG-CoA reductase inhibitors (statins) PPAR- ligands (fibrates) -Increased Blood Pressure: Inhibitors of the renin – angiotensin system B-Blockers Calcium channel antagonists

7 Exercise and Mobilization Nutrition

8 Anesthesia and Analgesia Volatile anesthetics Intravenous induction agents Opioids Neuraxial blockade

9 Thank you


Download ppt "Metabolic Syndrome By: Dr.AP.Ahmed el-Shaer Dr.Mohamed El-Zayat."

Similar presentations


Ads by Google