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Prospective Urban and Rural Epidemiology Study PURE Patricio López-Jaramillo, MD, PhD Lina Patricia Pradilla MD National Coordinator Colombia.

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Presentation on theme: "Prospective Urban and Rural Epidemiology Study PURE Patricio López-Jaramillo, MD, PhD Lina Patricia Pradilla MD National Coordinator Colombia."— Presentation transcript:

1 Prospective Urban and Rural Epidemiology Study PURE Patricio López-Jaramillo, MD, PhD Lina Patricia Pradilla MD National Coordinator Colombia

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5 PURE - URBAN Bucaramanga 300 subjects Sampling by blocks All economical social levels representated 01 1XX XXX 01

6 PURE - RURAL 317 subjects Included three areas: –Aratoca (01 2XX) –Barichara (01 3XX) –Villanueva (01 4XX)

7 STATUS OF COLOMBIA Applied Surveys URBANRURAL MEN93126 WOMEN242191 NON- RESPONDER 200 TOTAL355317

8 STATUS OF COLOMBIA Examinated population URBANRURAL MEN87126 WOMEN213191 TOTAL300317

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10 MALE Urban (n=87)Rural (n=126) p MeanSDMeanSD Age51.89.35010NS Systolic BP131.017.4133.418.4NS Diastolic BP82.410.982.510.8NS Weight75.811.267.610.9<0.001 Height167.86.3167.86.48NS BMI26.83.3243.7<0.001 Waist90.29.385.69.970.0001 Hip97.16.991.78.2<0.001 W/H ratio0.920.060.930.09NS Glycemia98.621.685.616.5<0.0001

11 FEMALE Urban (n=213)Rural (n=191) p MeanSDMeanSD Age51.09.849.99.5NS Systolic BP128.123.0134.222.20.0019 Diastolic BP79.911.083.412.70.0032 Weight65.713.060.510.60.0001 Height154.16.3154.26NS BMI27.75.525.44.2<0.0001 Waist81.011.580.710.3NS Hip99.59.895.29.2<0.0001 W/H ratio0.810.070.840.07<0.0001 Glycemia96.720.287.619.6<0.0001

12 MALE Urban (n=87)Rural (n=126) p MeanSDMeanSD Arm30.92.827.53<0.0001 Calf36.63.335.23.20.0016 Head56.11.655.220.0001 Grip Strenght 36.17.734.47.5NS FEMALE Urban (n=87)Rural (n=126) p MeanSDMeanSD Arm30.44.327.33.1<0.0001 Calf35.53.534.23.80.0009 Head541.353.41.80.0001 Grip Strenght 22.34.924.35.10.0001

13 Prevalence Blood Pressure ≥135 / ≥85 TotalUrbanRuralp Total sample (%) 276 (44.7) 124 (44.9) 152 (55.0) 0.0913 Men (%) 108 (50.9) 45 (41.6) 63 (58.3) 0.8495 Women (%) 168 (41.5) 79 (47.0) 89 (52.9) 0.0529 p value: Х 2 test urban vs rural

14 Prevalence Obesity Body Mass Index > 30Kg/m 2 TotalUrbanRuralp Total sample (%) 101 (16.3) 71 (70.2) 30 (29.7) <0.0001 Men (%) 24 (11.2) 16 (66.6) 8 (33.3) 0.0063 Women (%) 77 (19.0) 55 (71.4) 22 (28.5) 0.0003 p value: Х 2 test urban vs rural

15 Prevalence Abdominal Obesity Waist Circumference TotalUrbanRuralp Men* (%) 78 (36.7) 45 (57.6) 33 (42.3) <0.0001 Women** (%) 192 (47.5) 103 (53.6) 89 (46.3) 0.724 * Men: Waist circumference ≥ 90 cm **Women: Waist circumference ≥ 80 cm p value: Х 2 test urban vs rural

16 Prevalence of Fasting plasma glucose >100 mg/dl TotalUrbanRuralp Total sample (%) 121 (19.6) 89 (73.5) 32 (26.4) <0.0001 IFG (%) 93 (15.0) 69 (74.1) 24 (25.8) <0.0001 Type 2 DM(%) 28 (4.0) 20 (71.4) 8 (28.5) 0.0135 p value: Х 2 test urban vs rural

17 Impaired Fasting Glucose TotalUrbanRuralp Male (%)27 (12.6)15 (74.0)7 (25.9)0.0002 Female (%)66 (16.3)49 (74.2)17 (25.7)0.0001 Type 2 Diabetes Mellitus Male (%)7 (3.2)5 (71.4)2 (28.5)0.0942 Female (%)21 (5.2)15 (71.4)6 (28.5)0.0778 p value: Х 2 test urban vs rural

18 LESSONS LEARNED Urban: 1 month to complete all study in 300 subjects Rural: 1.5 month Personal: six ( 2 MDs, 3 nurses, 1 laboratory technician, all full time)

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