1. Presentation on Longhorn Vaccine & Diagnostics LLC PrimeStore® Suite of Products and Pipeline
1747 Citadel Plaza, Suite 206, San Antonio, Texas Bethesda Metro Center• Suite 905 • Bethesda, MD
Phone: (210)

2. Issues with Specimen Collection
Transport
< 4 Days: 4˚C packs
Laboratory testing
Transport Medium: REMEL, Copan, BD
or raw clinical specimen
Sample pre-treatment
Requires cold chain (4˚C packs or -70˚C dry ice) - $$$
Samples are viable and potentially infectious
Shipment restrictions---hazardous materials and packaging,
special handling - $$$
Quality control, i.e., temperature, transport monitoring
documentation
Stabilization/preservation of DNA/RNA from sample,
short transport window
> 4 Days: Dry Ice

3. PrimeStore® Molecular Transport Media
Target: “From Sputum to Sequencing”
No BSL3?
No power?
No cold chain?
No timely specimen transportation?
No Problem!
PrimeStore® MTM, the Safe, Reliable, Accurate, Affordable Collection-to-Detection System
“The Front-End for all Molecular Diagnostics”

4. PrimeStore MTM™ Advantages:
Collect and transport at ambient temperature
Ready for storage (in collection tube)
Kills microbes, destroys nucleases (DNase/RNase) and stabilizes and preserves DNA/RNA
Enhances nucleic acid testing sensitivity
Compatible with silica-based extraction methodologies including spin columns and bead-based extraction kits

5. PrimeStore MTM™ Advantages:
Compatible with multiple extraction kits/platforms
Ambion, Qiagen (including robotic extraction)
Roche MagnaPure and LightCycler
Life Technologies 7000/7500
Others (i.e. BioMerieux, BioRad)
Hain GenoType MTBDRplus Assay
Facilitates POC detection or high throughput testing (fixed or mobile diagnostic laboratories)

6. “From Sputum to Sequencing”
Swab in PS
Transport
Lab
Safe, ambient
temperature shipping
Sputum Specimen
Collection
PrimeStore MTM
Ion Torrent
Laboratory Preparation
Extraction
PCR
Sample processing