1. SCIENTIFIC PROGRAM OF THE CME COURSE TO BE HELD IN FLORENCE May 24 TH –May 25 TH 2010 GLOMERULAR DISEASES AND TRANSPLANTATION: SIMILARITIES IN PATHOGENETICAL MECHANISMS AND IN TREATMENT APPROACHES

2. May 24 th 14.00 – 18.30 14.00-14.40 Innate Immunity as trigger of renal damage. Focus on complement activation in glomerular diseases (Daha M) 14.40-15.10Activation of complement in humoral rejection (Regele H, Vienna) 15.10-15.30Discussion

3. 15.30-16.00 Toll-like receptors activation and glomerular diseases (Anders JH) 16.00-16.30 Role of dendritic cells in glomerular diseases and renal transplantation (Castellano G, Bari) 16.30-17.00 Discussion 17.00-17.30B cells and antibody network in glomerular diseases ( Ronco P, Paris) 17.30-18.00B cells and antibody network in renal transplantation (Cozzi E) 18.00-18.30 Discussion

4. May 25 th 8.00- 13.00 Therapeutical approaches to glomerular diseases and renal graft dysfunction 8.00-8.20 NFkB and proteasome modulation of transcription factors in glomerular diseases and renal transplantation (Coppo R) 8,20-8.40: Suppressors of Cytokine Signalling (SOCS): a new therapeutic target (Egido J) 8.40- 9.10Growth factors: Biomarkers and therapeutic targets (Floege J) 9.10-9.40 Discussion

5. 9.40– 10.10Proliferation signal inhibitors in nephrology and renal transplantation ( Campistol J, Barcellona) 10.10– 10.402° signal blockade in transplantation and renal diseases ( Grinyo J, Barcellona) 10.40-11.10 Discussion Coffee break 11.10-11.30 11.30 –12.00B cells inhibition in glomerular diseases (Jayne D, London) 12.00– 12.30B cells and antibody network inhibition in renal transplantation ( Salvadori M / Bertoni E, Florence) 12.30- 13.00 Discussion