1. Digestive system 1.Digestive system general feature 2.Oesophagus 3.Stomach 4.Large and small intestine 5.Liver 6.Pancreas

2. Digestive tube general structure

3. Digestive tube wall I. Mucosa: 1. Epithelium 2. Lamina propria 3. Muscularis mucosae II. Submucosa III. Muscularis externa IV. The outer tunica (adventitia or serosa)

4. Oesophagus

5. Stomach

6. Pyloric stomach

7. Small intestine

8. Villus-crypt system

9. Intestinal endocrine cell

10. Duodenum

11. Large intestine

12. Appendix

13. Rectum

14. Regeneration of epithelium

15. Liver Pancreas

16. Function of liver : 1. Syntesis: Bile Plasma proteine Plasma lypoproteines (vitamine K, D, E, A, cholesterine) 2. Detoxication 3. Destruction of spent red cell and reclamation of their constituens 4. Universal haemopoetic organ 5. Endocrine - somatomedine

17. LIVER & Pancreas LIVER Bile Hepatic artery Portal vein GI worm Hepatic veins Liver is the blood-processing glandular intermediary between you and your G-I worm (tract) that determines blood quality in two ways METABOLIC by Hepatocytes PROTECTIVE by Kupffer cells (M  s) W Beresford

18. Liver vasculature

19. Liver lobule

20. Liver specimen

21. Liver specimens

22. HEPATIC PARENCHYMA epithelial working tissue Plate of hepatocytes SINUSOID Plate of hepatocytes Endothelial cells Space SINUSOID Kupffer cell blood

23. CELL TYPES & ARRANGEMENT OF LIVER Microvilli Hepatocytes in plates Bile canaliculus SPACE OF DISSE Fenestrated Endothelial cells SINUSOIDKupffer cell STELLATE CELL HEPATOCYTE ENDOTHELIAL CELL KUPFFER CELL STELLLATE CELL

24. Hepatocyte, blood capilaries, bile canaliculus

25. Hepatocyte

26. bile canaliculus

27. Hepatocyte, blood capilaries, bile canaliculus

28. Schema of clasiccal and portal lobules and liver acinus

29. gallbladder

30. Epithelium of gallbladder

31. pancreas

32. Acinus and duct of pancreas

33. Homogenic and zymogenic zones

34. pancreatocyte

35. Langerhans islets

36. Classification of insulocytes: В- insulocytes – insulin А- insulocytes– glucagon D- insulocytes– somatostatin D 1 -insulocytes– VIP (vasoactive intestinal peptide) РР or F-insulocytes– pancreatic polypeptide