1. PROTON NUCLEAR MAGNETIC RESONANCE (H 1 NMR)

2. Terms used in an NMR spectrum. Downfield Upfield Deshielded protons Shielded protons Low induced field High induced field Larger  Smaller   values

3. Information from the 1H NMR Spectrum. Four different features of a 1H NMR spectrum provide information about a compound’s structure: Number of signals. Position of signals. Intensity of signals. Splitting of signals.

4. Chemical Shift Values H Environment δH Environment δ (CH 3 ) 3 Si 0 (defined)R-COOCH ~3.5-4.5 Alkane -CH 3 ~0.9C=C-H ~4.5-6 -CH 2 - ~1.3 -CH- ~1.6Ar-H ~6.5-8 (C, N, O)=C-CH ~1.5-2.5R-CHO ~9-10 -C≡C-H ~2.5R-COOH ~10-12 (N, O)-CH ~2.5-4R-OH ; R-NH ~1-5

5. Proton NMR Spectra - Methanol

6. Proton NMR Spectra – chloromethyl methyl ether

7. Anisotropic Effects - Alkenes

8. Anisotropic Effects - Aromatic

9. Anisotropic Effects - Alkynes

10. Proton NMR Spectra - Toluene

11. Proton NMR Spectra – o-Xylene

12. Proton NMR Spectra – Acetic acid

13. Proton NMR Spectra – 4-hydroxy-4-methyl-2-pentanone

14. Proton NMR Spectra – Methyl acetoacetate

15. Proton NMR Spectra –  -chloroacetophenone

16. Proton NMR Spectra – 1,1,2-Tribromoethane

17. Proton NMR Spectra – 1-bromopropane

18. Proton NMR Spectra – 1,1,-dichloro-2,2-diethoxyethane

19. Proton NMR Spectra – Isopropyl Methyl ketone

20. END H 1 NMR