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Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity by Alice P. Liou, Melissa Paziuk, Jesus-Mario Luevano, Sriram.

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Presentation on theme: "Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity by Alice P. Liou, Melissa Paziuk, Jesus-Mario Luevano, Sriram."— Presentation transcript:

1 Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity by Alice P. Liou, Melissa Paziuk, Jesus-Mario Luevano, Sriram Machineni, Peter J. Turnbaugh, and Lee M. Kaplan Sci Transl Med Volume 5(178):178ra41-178ra41 March 27, 2013 Published by AAAS

2 Fig. 1 Schematic of experimental design. Alice P. Liou et al., Sci Transl Med 2013;5:178ra41 Published by AAAS

3 Fig. 2 Phenotypic data from the RYGB mouse model. Alice P. Liou et al., Sci Transl Med 2013;5:178ra41 Published by AAAS

4 Fig. 3 RYGB causes marked, rapid, and sustained changes in gut microbial ecology that are independent of weight and diet. Alice P. Liou et al., Sci Transl Med 2013;5:178ra41 Published by AAAS

5 Fig. 4 Bacterial taxonomic groups that discriminate among RYGB-, SHAM-, and WMS-derived samples. Alice P. Liou et al., Sci Transl Med 2013;5:178ra41 Published by AAAS

6 Fig. 5 Relative abundance of bacterial taxa throughout the gastrointestinal tract of RYGB, SHAM, and WMS mice. Alice P. Liou et al., Sci Transl Med 2013;5:178ra41 Published by AAAS

7 Fig. 6 Decreased weight and adiposity is transmissible via the gut microbiota. Alice P. Liou et al., Sci Transl Med 2013;5:178ra41 Published by AAAS

8 Fig. 7 SCFA levels are consistent between donor and recipient animals. Alice P. Liou et al., Sci Transl Med 2013;5:178ra41 Published by AAAS


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