1. Adding a Biosocial Component to Understanding Society Research Methods Festival Session 56 – Understanding Society July 2010 Stephanie McFall

2. Objectives of presentation Provide overview of biosocial data collection for Understanding Society Put in context of other health information

3. Biosocial Understanding Society Collection of biomarkers part of overall study objectives Funds from Large Facilities Capital Fund to support collection from part of the sample Needs to move quickly, to complete collection by 2012 Funds for range of biomarkers, anthropometric and functional measures from adults Will collect from BHPS sample and from random sample of adults from new samples Seek future support for additional collections

4. Measures in 2 phases Survey nurses Whole blood sample For DNA and analytes HbA1c, cholesterol, CRP, Cystatin-C Anthropometry Height, weight, waist circumference, biometric impedance Functional measures Blood pressure, grip strength, lung function Non-clinical interviewers Saliva samples for DNA Dried blood spots HbA1c, CRP, cholesterol, Cystatin-C Anthropometry Height, weight, waist circumference, biometric impedance Functional measures Blood pressure, grip strength

5. Getting a quick start Build on experience and resources of NatCen, our survey organization Workforce Measurement protocols Training methods Build on consultation process

6. Eligible: Full CAPI interview Adult Gen. pop. W2 (2010) BHPS W3 (2011) Nurse visit ~ 5 mo. later Token of appreciation to respondent Tissue samples (Blood) Separate written consents Measures Oral consent Transport to storage facility Sequence in nurse visit

7. Upcoming pilot of interviewer collection – Autumn 2010 Focus on performance of core biomeasures Acceptability to interviewers and respondents Refine measurement procedures, e.g., timings Trial run of interviewer training procedures Preliminary information about quality of measures 100 adults and 20 interviewers Participants from NatCen Omnibus Survey willing to be contacted for further research Support large scale implementation of interviewer collection (potentially) in Summer 2011

8. Health component of adult questionnaire Interview SF-12 including self-rated health Height & weight Long-standing illness or disability Type of disability or infirmity Diagnosed health conditions Health behaviours (diet, exercise, smoking) Self-completion GHQ-12 Quality and duration of sleep Life/health satisfaction The Warwick-Edinburgh Mental Well-being Scale Alcohol consumption

9. Youth questionnaire health component Strengths and Difficulties Questionnaire Health behaviours – diet, exercise, smoking, alcohol, drugs Self-reported height and weight Self-rated health

10. Linkage of health records Consent asked of adults and about children by responsible adult Request for past, current and future records Records on health registration Hospital admission information Dates, diagnoses, treatments, procedures, waiting times Specific conditions, e.g., cancer Potentially useful in extending scope of interview and biomeasure data – link life histories to health care use, diagnoses, mortality

11. Conclusion Variety of biomeasures ranging from genetic to functional to physical measurements Rich socio-economic data provides opportunity to assess exposure and antecedent factors of health status, understanding disease mechanisms and pathways, household and socioeconomic effects Interaction of social and biological factors in behaviour Support social science and biomedical research and research linking the two Resource for wide range of interdisciplinary research