1. 2. What are the common and uncommon symptoms of MVP?

2. Population group 14 - 30 years old Women Increased familial incidence Reference: Fauci et al. Harrison’s Principles of Internal Medicine, 17 th ed.

3. Common Symptoms * Patients are mostly asymptomatic Others may manifest with: Easy fatigability Shortness of breath Palpitation Non-anginal chest pain Light-headedness Syncope Reference: Fauci et al. Harrison’s Principles of Internal Medicine, 17 th ed.

4. Uncommon Symptoms Transient ischemic attacks Congestive cardiac failure Endocarditis – in MR associated with MVP Sudden death Reference: Fauci et al. Harrison’s Principles of Internal Medicine, 17 th ed.

5. Symptoms related to autonomic dysfunction are usually associated with genetic inheritance: – Anxiety – Panic attacks – Arrhythmias – Exercise intolerance – Palpitations – Atypical chest pain – Fatigue – Orthostasis – Syncope or presyncope – Neuropsychiatric symptoms Thakkar, B. (2008) Mitral Valve Prolapse

6. Symptoms related to progression of mitral regurgitation : – Fatigue – Dyspnea – Exercise intolerance – Orthopnea – Paroxysmal nocturnal dyspnea (PND) – Progressive signs of congestive heart failure (CHF) Thakkar, B. (2008) Mitral Valve Prolapse