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A Randomized Phase 2 Trial Comparing Efficacy of the Combination of the PARP-inhibitor Olaparib and the Anti-angiogenic Cediranib Against Olaparib Alone in Recurrent Platinum- sensitive Ovarian Cancer Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Background: cediranib and olaparib are active agents in ovarian cancer Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Cediranib and olaparib have synergistic activity in vitro Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Phase 1 study of cediranib and olaparib demonstrated activity in ovarian cancer patients Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Study Objectives Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Study Design Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Key eligibility criteria Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Statistical Considerations Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Study Status and Data Analysis Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Patient Characteristics Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Primary Outcome: Cediranib/olaparib significantly increased PFS compared to olaparib alone Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Secondary Outcome: Cediranib/olaparib significantly increased overall response rate (ORR) compared to olaparib alone Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Cediranib/olaparib significantly increased PFS in patients without a BRCA mutation Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Treatment-related Adverse Events Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Tolerability of cediranib/olaparib combination Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Conclusions Presented By Joyce Liu at 2014 ASCO Annual Meeting
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Acknowledgments Presented By Joyce Liu at 2014 ASCO Annual Meeting
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