1. Technology Transfer at Case Western Reserve University Casey Porto, Assoc. V. P.

2. Our Mission To lead the successful commercialization of ideas created by people at CWRU through: —Licensing —Start-up of new companies

3. Our Operating Philosophy Focus on innovation marketing vs. technology Targeted approach Select and concentrate on winners Operate as a business cost recovery Active involvement new company formation

4. CWRU Externally Sponsored Project Awards – FY02 * ($Millions) Medicine$17877% Clinical Depts. $96; Basic Science Depts. $68 Engineering$3013% Biomed.Eng. $10, Mat.S&E $4, Macromolec. Sci. $4 Arts and Sciences$146% Physics $3, Chemistry $4, Biology $3 Professional Schools$83% Nursing $4.5; Mandel Sch.Appl.Soc.Sciences $2; University General $31% TOTAL$233100% * approximately 90% for research and development

5. O F F I C E O F T E C H N O L O G Y T R A N S F E R The Process Phase 1 - Evaluation Commercial Merit (Pre-Marketing) Intellectual Property Protection Technical Merit Receive/Solicit Ideas from CWRU People “Invention Disclosures” Phase 2 - Commercialization Sell LicensesObtain IP ProtectionAdditional R&D

6. What we’ve done since July 1, ‘02 100 MTAs executed 60 CDAs executed 18 SRAs assisted, $324,000 leveraged 6 Licenses, 2 Options Currently Negotiating ~ 10 Licenses/Options 64 New Invention Disclosures Revenue year-to-date: $5.2 Mil

7. Accomplishments in last 18 months Combined 3 prior tech transfer functions into one central office Hired 5 new professional staff, 5 support staff Installed and populated new database (JAKE) Redesigned website and invention disclosure form Moved into new office space—centrally located Published first annual report; quarterly newsletters In FY02, increased revenue 50% over prior year; FY03 projected to be almost double FY02

8. Incubation Services Organizer’s function Start-up documentation package and license Recruitment of management team Physical incubation services Development of business plan Business advice and assistance Financial support

9. Case Technology Ventures Multi-million $ “pre-seed-stage” fund managed by TTO at Case Western Reserve University Start-ups based on University-owned IP Recently awarded $1 Mil from State of Ohio Technology Action Fund Provides capital (50-250k) to start-ups for: –Prototype development –Management team recruiting –Startup legal expenses –Business plan development –Facilities

10. Our Goals Bring more CWRU technologies to market Encouragement of university spin-off companies Over-all financial results for the university Technology Transfer as a strategy for development, industrial sponsored research and recruiting/retaining the best research talent Proactive emphasis of regional economic development