1. Day 2 Seminar Types of research articles

2. Original research article new knowledge for the first time

3. Other types of articles in journals: Case report Review article Editorial material: Editorials Commentaries Viewpoints Letter to editor Book or media review

4.  Observational studies ◦ Cross-sectional / prevalence ◦ Case-control / retrospective ◦ Cohort / prospective  Experimental studies ◦ Controlled clinical trials

5. Hierarchy of evidence 1.N of 1 randomized control trial 2.Systematic reviews of randomized control trials 3.Single randomized control trial 4.Systematic review of observational (cross-sectional, cohort, or case-control) studies 5.Single observational (cross-sectional, cohort, or case-control) study 6.Physiologic studies (studies of blood pressure, cardiac output, exercise capacity, bone density, etc) 7.Unsystematic clinical observations (case series, case report)

6. Cross-sectional study Case control study Cohort study sadašnjost prošlostbudućnost Historical cohort study Experimental research Time of study group formation Time of data collection PastPresentFuture

7. Hierarchy of evidence http://www.cebm.net/index.aspx?o=1025 Centre for Evidence Based Medicine, University of Oxford Levels of evidence for: Therapy / Prevention, Aetiology / Harm Prognosis Diagnosis Differential diagnosis / symptom prevalence study Economic and decision analyses

8. http://www.ted.com/talks/ben_goldacre_battli ng_bad_science?language=en