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Color Vision Dr Taha Sadig Ahmed MBBS. PhD MAANEM
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History of color vision Newton (1704) used a prism to show that sunlight was composed of light with all colors in the rainbow. He defined it as the spectrum.
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History of color vision Primary colors: 723-647 575-492492-450 Thomas Young 1807: primary colors: when mixed >>> white or any other color
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Mixing colors
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Photopic vision (CONES) Helmholtz..1860: The three primary colors are perceived by three photoreceptor pigments (with broad absorption curves) White light is produced by mixing three colours
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Cone wavelength ranges SML Wavelength (nm) Relative absorption 400500600 700
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Photopic vision (CONES) Cone pigments: three kinds 565 535440
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Photopic vision Young Helmholtz theory Color vision is subserved by three types of cones, each containing a photoreceptor pigment most sensitive to one primary color 1.Cones (contain red-sensitive pigment) 2.Cones (contain green-sensitive pigment) 3.Cones (contain blue-sensitive pigment) in the fovea centralis
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Cone wavelength ranges SML Wavelength (nm) Relative absorption 400500600 700
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Color Blindness Weakness or total blindness in detecting a primary color: Definitions: 1.Trichromats: see the 3 1ry colors 2.Dichromats: blind to one 1ry color 3.Monochromats: have color pigment
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Color Blindness –cont. Prot …… Red Deuter …. Green Trit …… Blue Anamoly …weakness Protanamoly Deuteranamoly Trichromats Tritanamoly
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Color Blindness –cont. Anamoly …weakness Anopia …. Total loss Protanopia Deuteranopia Dichromats Tritanopia
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Trichromatic/dichrom atic color vision
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Color Blindness –cont. Prevalence: males ………….8% females …. 0.4% Inheritance: sex-linked due abnormal gene in the X chromosome
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Electrophysiology of Vision
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Light Change in photopigment Metarhodopsin II Activation of transducin Activation of phophodiesterase Decrease IC cyclic GMP Closure of Na channels Hyperpolarization of receptor Action potential in optic nerve fibres
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Photoreception
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Figure 17.15 Bleaching and Regeneration of Visual Pigments
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Electrophysiology of Vision Electric recording in Retinal cells: Bipolar cells: Hyper- & Depolarization Horizental cells: Hyper- & Depolarization Amacrine cells: Depolarizing potential Ganglion cells: Depolarizing potential
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