1. 9.2 Mitosis and Cytokinesis Objective: 5(A) Describe the stages of the cell cycle, including DNA replication and mitosis, and the importance of the cell cycle to the growth of organisms.

2. Eukaryotic cells reproduce by mitosis, the process of nuclear division, and cytokinesis, the process of cytoplasm division. Section 2: Mitosis and Cytokinesis K What I Know W What I Want to Find Out L What I Learned

3. 5(A) Describe the stages of the cell cycle, including deoxyribonucleic acid (DNA) replication and mitosis, and the importance of the cell cycle to the growth of organisms. 4(B) Investigate and explain cellular processes, including homeostasis, energy conversions, transport of molecules, and synthesis of new molecules. Mitosis and Cytokinesis Copyright © McGraw-Hill Education

4. Essential Questions What are the events of each stage of mitosis? What is the process of cytokinesis? Mitosis and Cytokinesis Copyright © McGraw-Hill Education

5. Review life cycle New prophase sister chromatid centromere spindle apparatus metaphase anaphase telophase Mitosis and Cytokinesis Copyright © McGraw-Hill Education Vocabulary

7. Mitosis and Cytokinesis Copyright © McGraw-Hill Education Mitosis During mitosis cell’s replicated genetic material separates and the cell prepares to split into two cells. The key activity of mitosis is the accurate separation of the cell’s replicated DNA. Mitosis: Increases the number of cells in a multicellular organism as it grows Replaces damaged cells

8. Mitosis and Cytokinesis Copyright © McGraw-Hill Education The Stages of Mitosis Prophase Prophase is the first and longest stage of mitosis. Cell’s chromatin tightens/condenses into chromosomes. Sister chromatids are structures that contain identical copies of DNA. The sister chromatids are attached at the centromere.

9. Mitosis and Cytokinesis Copyright © McGraw-Hill Education The Stages of Mitosis Prophase As prophase continues, spindle fibers, centrioles, and aster fibers form a spindle apparatus. The spindle apparatus attaches to each of the sister chromatids.

10. Mitosis and Cytokinesis Copyright © McGraw-Hill Education The Stages of Mitosis Metaphase The second stage of mitosis is metaphase – the shortest phase. Sister chromatids are pulled along the spindle apparatus toward the center of the cell. They line up in the middle of the cell.

11. Mitosis and Cytokinesis Copyright © McGraw-Hill Education The Stages of Mitosis Anaphase During anaphase, the chromatids pull apart. The microtubules of the spindle apparatus begin to shorten. The sister chromatids separate. The chromosomes move toward the poles of the cell.

12. Mitosis and Cytokinesis Copyright © McGraw-Hill Education The Stages of Mitosis Telophase Telophase is when the chromosomes arrive at the poles and begin to decondense. Two new nuclear membranes begin to form and the nucleoli reappear. The spindle apparatus disassembles.

13. Mitosis and Cytokinesis Copyright © McGraw-Hill Education Cytokinesis After the two daughter nuclei have formed, cells undergo cytokinesis. In animal cells, microfilaments constrict/pinch off to form two cells. In plant cells, instead of pinching in half, a new structure called the cell plate forms between the two daughter nuclei.

14. Visualizing the Cell Cycle Mitosis and Cytokinesis Copyright © McGraw-Hill Education

15. Mitosis and Cytokinesis Copyright © McGraw-Hill Education Review Essential Questions What are the events of each stage of mitosis? What is the process of cytokinesis ? Vocabulary prophase sister chromatid centromere spindle apparatus metaphase anaphase telophase