1. The Origin of Cells 1.5

2. Understanding Applications Nature of Science Cells can only be formed by division of pre-existing cells The first cells must have arisen from non-living material The origin of eukaryotic cells can be explained by the endosymbiotic theory Evidence from Pasteur’s experiments that spontaneous generation of cells & organisms does not now occur on Earth Testing the general principles that underlie the natural world: the principle that cells only come from pre-existing cells needs to be verified.

3. Review the Cell Theory  All living things are made of cells  Cells are the smallest unit of life  All cells come from pre-existing cells

4. Cell Theory  Has been modified since the 1800’s  Does not mention how the first cells arose

5. Spontaneous Generation  Life can be created from non- living matter  Greek philosopher Theophrastus  Plant Silphium had sprung from soil where it had never been before

6. Spontaneus Generaton  Aristotle  Wrote how insects formed from dew falling on leaves or from the hair, flesh or faeces of animals.

7. Maggots develop on meat only if they came in contact with it. Boiled soup in 8 containers, sealed 4 & left 4 open. Redi Spallanzani

9. Pasteur 1.Nutrient broth boiled. 2.Sterile broth placed in 3 flasks. 3.A sample of each flask was transferred to a plate containing solid medium & incubated. 4.Only flask with bacteria was _____

10. So where did the first cells come from?

11. Endosymbiosis