1. the biomarker company™
Delivering Biomarker Discovery Data to
Customers and Collaborators using Posters
Keith Joho, Ph.D.
Vice President, Informatics and Bioanalytical Operations

2. Low MW (Metabolome) Proteome Cytometry (SurroScanTM cytometer)
Biomarker Discovery
Her2
Cells
CD4+
T-cells
Clinical
Phenotype
Homocysteine
Cholesterol
PSA
CRP ?
Glucose TG
Insulin
HbA1C
Complex
Systems
Simple molecules
metabolites
carbohydrates
steroids
lipids
peptides proteins
protein complexes
Mass Spectrometry
Low MW (Metabolome) Proteome
Immunoassays
Cytometry (SurroScanTM cytometer)
eCRF, eMR
SurroMed Technologies:
Gene
chip
mRNA/genes
cells
patients

3. SurroMed Data Warehouse
Oracle
Cytometry
LIMS
Clinical
eCRF
EMR
ELISA
Mass Spectrometry
Proteomic
Metabolomic

4. SurroStat™ Architecture
CLIENTS
HTTP/ HTTPS
Web Server
S-Plus AS
Sun ONE
J2EE Application
Server
Oracle
Posters
Decision Site
JSP
EJB
Servlets
SurroStat™
JDBC

5. SurroStat™ Spotfire Integration

6. SurroMed Posters Architecture
Customer A
Publish
HTTPS
Customer B
DecisionSite
Server
(Production)
Posters
DecisionSite
Server
(Internal)
Posters
Data Warehouse
HTTPS
HTTPS
Customer C
Posters
Repository
User Profile
Database
Posters
Repository
User Profile
Database
Surromed
Internal
Network
Internet
DMZ