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Figure 1. Figure 2 ab p=0.0009 p=0.0014 *** Figure 3 a *** b cFos TP53 Beta actin cFos TP53 Beta actin.

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Presentation on theme: "Figure 1. Figure 2 ab p=0.0009 p=0.0014 *** Figure 3 a *** b cFos TP53 Beta actin cFos TP53 Beta actin."— Presentation transcript:

1 Figure 1

2 Figure 2 ab p=0.0009 p=0.0014

3 *** Figure 3 a *** b cFos TP53 Beta actin cFos TP53 Beta actin

4 UntreatedCXR9HXR9 Figure 4 b a c ** EA LA % cells ** * *

5 Figure 5 IC50 (  M) Decreasing sensitivity 16 23 33 42 48 51 p=0.0024 p<0.0001 **** * Decreasing sensitivity 16 23 33 42 48 51 p=0.0243p=0.0008p<0.0001p=0.0012 *** a b r 2 = 0.9778 p=0.0002 SKBR3 MB231 MCF7 ZR75.1 UACC MCF10a NBT (predicted) cd

6 Figure 6 a b c p=0.004 p<0.001 p=0.0027 CXR9HXR9 S T d

7 Online resource 1

8 CXCL1 5.13 FOSB 4.04 ATF3 3.61 AREG 3.61 TNFAIP3 3.70 NR4A21 3.32 NR4A3 3.08 ZFP36 3.07 CD83 2.73 UPP1 2.53 PPP1R15A 2.82 CD86 2.73 CCL20 2.37 EGR1 2.65 ARL14 2.24 TNF 3.21 KLF2 2.07 DUSP5 2.26 IL1RL1 1.86 NCOA7 2.46 456789 0250500750100012501500 * TGATTAAT(G/T)(G/A) Online resource 2 Log fold increase in transcription by HXR9 Base pairs 5’ from transcription start site

9 a b c d e f Online resource 3 p=0.0126p=0.0170 p=0.3488 p=0.8836p=0.9754 p=0.2378p=0.0688 h g p=0.7544 p=0.8344

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