1. 1 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009

2. 2 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data sources: IMS Health and the Centers for Medicare & Medicaid Services © 2012 MEDICARE

3. 3 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 1 Enrollment figures are year-end totals, and do not include Medicare Advantage enrollees in Puerto Rico and U.S. territories. 2 “Other” includes Cost, MSA, PSO (state license) and Pilot plans. MEDICARE

4. 4 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 HOSPITAL-BASED MEDICARE 1 Percentages do not sum to 100%, because there is also an “other” payer category that is not shown, which includes self-pay, charity, workers’ compensation and unknown payer sources

5. 5 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 MEDICARE 1 Only HMOs that enroll Medicare beneficiaries are included. 2 Ambulatory visits differ from physician encounters. Ambulatory visits are visits by an HMO member to an HMO clinic or physician’s office that do not require the services of a physician. Such visits are usually made for tests, prescription refills, immunizations, etc. The term “physician encounter” is self-explanatory.

6. 6 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 MEDICARE

7. 7 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 MEDICARE Data source: IMS Health © 2012 1 Data are as of midyear 2011, and represent the numbers/percentages of prescriptions dispensed, by drug class, to all patients.

8. 8 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 MEDICAID Data source: IMS Health © 2012 2 Enrollment totals for 2010 and 2011 are from June of that year.

9. 9 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 MEDICAID 1 National estimates were calculated based on previous years of national Medicaid enrollment growth and the shifting of Medicaid recipients to managed care in a number of largely populated states in 2010.

10. 10 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 MEDICAID 1 Only HMOs that enroll Medicaid recipients are included. 2 Ambulatory visits differ from physician encounters. Ambulatory visits are visits by an HMO member to HMO clinic or physician’s office that does not require the services of a physician. Such visits are usually made for tests, prescription refills, immunizations, etc. The term “physician encounter” is self-explanatory.

11. 11 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 HOSPITAL-BASED MEDICAID

12. 12 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 MEDICAID Data source: IMS Health © 2012 1 Data are as of midyear 2011, and represent the numbers/percentages of prescriptions dispensed, by drug class, to all patients.

13. 13 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 MEDICAID Data source: IMS Health © 2012 1 Data are as of midyear 2011, and represent the numbers/percentages of prescriptions dispensed, by drug class, to all patients. 2 The total full price the pharmacy charges the patient for the product, regardless of the copayment situation. NOTE: “Out-of-pocket cost” is the actual amount paid by the patient for the individual prescription. This cost mainly includes copayments, but can also include tax, deductibles and cost differentials where applicable.

14. 14 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 MEDICAID Data source: IMS Health © 2012 1 Data are as of midyear 2011, and represent the numbers/percentages of prescriptions dispensed, by drug class, to all patients.

15. 15 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 LONG-TERM CARE Data source: IMS Health © 2012

16. 16 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 LONG-TERM CARE: NURSING HOMES Data source: IMS Health © 2012

17. 17 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 LONG-TERM CARE: HOME CARE AGENCIES Data source: IMS Health © 2012

18. 18 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 LONG-TERM CARE: HOSPITAL-BASED SNFs Data source: IMS Health © 2012

19. 19 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 LONG-TERM CARE: HOSPITAL-BASED SNFs

20. 20 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 LONG-TERM CARE: LTCPPs

21. 21 Managed Care Digest Series ®, © 2012 sanofi-aventis U.S., A SANOFI COMPANY US.NMH.12.09.009 Data source: IMS Health © 2012 LONG-TERM CARE: LTCPPs