2. Section 3 Objectives – page 211 Section Objectives Describe the role of enzymes in the regulation of the cell cycle. Distinguish between the events of a normal cell cycle and the abnormal events that result in cancer. Identify ways to potentially reduce the risk of cancer.

3. Section 8.3 Summary – pages 211 - 213 Normal Control of the Cell Cycle The cell cycle is controlled by ________ ________________and a set of enzymes that attach to the cyclin and become activated. Occasionally, cells lose control of the cell cycle. Proteins and enzymes control the cell cycle

4. Section 8.3 Summary – pages 211 - 213 Normal Control of the Cell Cycle Cancer is a malignant growth resulting from________________________________ This uncontrolled dividing of cells can result from:_______________________________ ____________________________________ ____________________________________ ____________________________________ ____________________________________

5. Section 8.3 Summary – pages 211 - 213 Normal Control of the Cell Cycle _______________production is directed by __________________ located on the chromosomes. A gene is a ____________________that controls the production of a______________________.

6. Section 8.3 Summary – pages 211 - 213 Cancer: A mistake in the Cell Cycle Currently, scientists consider cancer to be a ____________________________________ ____________________________________ that produce substances that are involved in controlling the cell cycle. Cancerous cells form masses of tissue called tumors that deprive normal cells of nutrients.

7. Section 8.3 Summary – pages 211 - 213 Cancer: A mistake in the Cell Cycle In later stages, cancer cells enter the ____________________________________ and spread throughout the body, a process called______________________, forming new tumors that disrupt the function of_____________________, organ systems, and ultimately, the ____________________.

8. Section 8.3 Summary – pages 211 - 213 The causes of cancer The causes of cancer are difficult to pinpoint because both _______________________and __________________________________ are involved.

9. Section 8.3 Summary – pages 211 - 213 The causes of cancer Environmental factors, such as__________________ ___________________ ___________________ ___________________ _________________ are all known to damage the genes that control the cell cycle.

10. Section 8.3 Summary – pages 211 - 213 The causes of cancer Cancer may also be caused by ____________________________________ that damage the genes.

11. Section 8.3 Summary – pages 211 - 213 Cancer prevention Physicians and dietary experts agree that diets ________________________and ________________________content can reduce the risk of many kinds of cancer. _______________________and _______________________ may also help prevent cancer.

12. Section 8.3 Summary – pages 211 - 213 Cancer prevention In addition to diet, other healthy choices such as ______________ ______________ and not using ______________ also are known to reduce the risk of cancer.

13. Chapter Summary – 8.1 Osmosis is the diffusion of water through a selectively permeable membrane. Cellular Transport Passive transport moves a substance with the concentration gradient and requires no energy from the cell.

14. Chapter Summary – 8.1 Active transport moves materials against the concentration gradient and requires energy to overcome the flow of materials opposite the concentration gradient. Cellular Transport Large particles may enter a cell by endocytosis and leave by exocytosis.

15. Chapter Summary – 8.2 Cell size is limited largely by the diffusion rate of materials into and out of the cell, the amount of DNA available to program the cell’s metabolism, and the cell’s surface area-to-volume ratio. Cell Growth and Reproduction The life cycle of a cell is divided into two general periods: a period of active growth and metabolism known as interphase, and a period that leads to cell division known as mitosis.

16. Chapter Summary – 8.2 Mitosis is divided into four phases: prophase, metaphase, anaphase, and telophase. Cell Growth and Reproduction The cells of most multicellular organisms are organized into tissues, organs, and organ systems.

17. Chapter Summary – 8.3 The cell cycle is controlled by key enzymes that are produced at specific points in the cell cycle. Control of the Cell Cycle Cancer is caused by genetic and environmental factors that change the genes that control the cell cycle.