1. HANC and Community Partners Overview November 20, 2007 Michael Petillo, Project Coordinator

2. What is HANC? HIV/AIDS Network Coordination Office established in 2004 with support from the DAIDS-funded HIV Clinical Research Trials Networks Directed by Dr. James Kublin and funded by DAIDS Work plan guided by DAIDS and six Network Principal Investigators Located at the Fred Hutchinson Cancer Research Center in Seattle, Washington, USA 2

3. What is HANC’s mission? Coordinated research Collaborative solutions Cross-Network communication 3 cross network coordination MTNINSIGHTIMPAACTHVTNHPTNACTG CHAVIDODIAVINICHDPAVE

4. Communicate Why is cross-network coordination important? Improved processes Increased efficiency Resource sharing 4 Collaborate Standardize Innovate

5. Leadership Network Leaders NLOG Laboratory LAB PI/Manager IQAPBMC QA Safety Lab QA TB Diagnostics Training Safety & EAE Admin- Fiscal Risk Reduction Counseling Evaluation Cross- Network EC SDMC DMC Harmonization Community Community Partners Community Training Recommendations 5 What does HANC do? Facilitates communication and information sharing for collaborative, international, cross-Network groups Helps to identify and connect groups that might not otherwise interact regularly, but have common interests or challenges Current cross-Network groups

6. HANC methods Connect individuals or groups with shared interests Define specific goals, objectives and timelines Coordinate working group activities Facilitate conference calls, meetings and discussions Provide administrative and logistical support tools Identify and report on successes and challenges 6

7. 7 What is Community Partners? A leadership group that was proposed and developed by community volunteers and staff, designed to represent cross-Network community research needs and priorities scientific agendas ethical conduct of clinical trials community education communication/information dissemination respect for community priorities continued community participation Funded by DAIDS as part of recent RFA and recompetition process

8. Community Partners Membership Structure Voting membership includes community representatives selected by each Network, as well as additional at large and regional reps. Network staff, DAIDS and HANC reps serve in a non-voting capacity.

9. Working groups of the CP - 1 Community Training Working Group: works to identify and develop programs to meet the training and support requirements of local CABs. Currently undertaking work in that respect Community Recommendations Working Group: working on the document ‘recommendations for community involvement in NIH DAIDS Clinical Trial Networks’. Work still in progress

10. Working groups of the CP - 2 Nominations Working Group: which handles nomination processes in the group. Currently saddled with the responsibility of identifying Co- Chairs for the group Scientific Priorities Steering Committee: Would focus on identifying scientific priorities of the community and articulating this to the Network and DAIDS leadership

11. Working groups of the CP – 3 Adhoc committees: there is the Open Letter on Sex and Gender working committee. The committee tries to work across the network to ensure that information on transgender issues are collected at the trial sites so as to ensure that transgender health related problems are identified and planned for.

12. AIDS Clinical Trials Group (ACTG) HIV Prevention Trials Network(HPTN) HIV Vaccine Trials Network (HVTN) International Maternal, Pediatric, Adolescent AIDS Clinical Trials (IMPAACT) International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) Microbicide Trials Network (MTN) Map of Community Partners Members’ Locations - September 2007

13. HANC contacts 13 Leadership: Jim Kublin, MD, MPH jkublin@fhcrc.orgjkublin@fhcrc.org Laboratory: Alissa Johnson ajohns2@fhcrc.orgajohns2@fhcrc.org Training & Evaluation: Christie Villa cvilla@fhcrc.orgcvilla@fhcrc.org Data Management: Alissa Johnson ajohns2@fhcrc.orgajohns2@fhcrc.org Community: Michael Petillo mpetillo@fhcrc.orgmpetillo@fhcrc.org Website: www.hanc.info