1. THE CELL MEMBRANE CHAPTER 5

2. Fluid Mosaic Model

3. Fundamental Architecture of Cell Membranes Phospholipid Bilayer Transmembrane Proteins Interior protein Network Cell Surface Markers ( glycoproteins and glycolipids)

4. How can we see the membrane? Electron Microscopy Freeze fracturing

6. Membrane Fluidity Saturated vs Unsaturated fats Bacteria Temperature

7. Proteins in the Membrane Transporters Enzymes Cell surface receptors Cell surface identity markers Cell-to-cell adhesion proteins Attachments to the cytoskeleton

9. Transmembrane Domains Alpha Helices, span membrane at least once

10. Pores Betapleated sheets

11. Passive Transport Across Membranes Moving Down a concentration gradient Diffusion

12. Proteins in Diffusion Channel Proteins Carrier Proteins –Make membrane selectively permeable

13. Ion Channels Can be gates 3 conditions determine net movement –Concentrations across membrane –Voltage difference –The state of the gate

14. Facilitated Diffusion Still Passive Diffusion rate depends on the amount of available receptors Can reach saturation Specific to certain molecules or ions Found in RBCs (glucose and Chloride HCO 3 )

15. Osmosis Movement of water across membranes Solvents vs Solutes Osmotic Concentration:Hyp ertonic vs Hypotonic vs Isotonic Aquaporins Hydrostatic Pressure

16. Methods of Maintaining Balance Extrusion- found in many single-celled eukaryotes….contractile vacoules Isomotic Regulation- organisms that live in the ocean Turgor- plant cells

17. Active Transport Uses Energy Moves against concentration gradient Uniporters vs symporters vs antiporters

18. Sodium Potassium Pump

19. Coupled Transport Uses ATP indirectly Uses the energy created by another transport to move a molecule up their concentration gradient ex. glucose

20. Endocytosis Cell takes in materials Phagocytosis Pinocytosis Can be Receptor mediated

21. Exocytosis Material leaves the cell