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Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction by A. E. Firth, B. W. Jagger,

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Presentation on theme: "Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction by A. E. Firth, B. W. Jagger,"— Presentation transcript:

1 Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction by A. E. Firth, B. W. Jagger, H. M. Wise, C. C. Nelson, K. Parsawar, N. M. Wills, S. Napthine, J. K. Taubenberger, P. Digard, and J. F. Atkins Open Biology Volume 2(10):120109 October 22, 2012 ©2012 by The Royal Society

2 Mass spectrometric analysis of the PA-X-GFP frameshift fusion protein. A. E. Firth et al. Open Biol. 2012;2:120109 ©2012 by The Royal Society

3 Predicted sites of ‘PAX-like’ +1 frameshifting in (a) fijiviruses, (b) chronic bee paralysis and Lake Sinai viruses, and (c) amalgamaviruses. A. E. Firth et al. Open Biol. 2012;2:120109 ©2012 by The Royal Society

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