1. Circ D

2. Case 52  Clinical : Male baby.

11.  Most popular diagnosis….

12.  Myofibromatosis (+/- infantile) 8.39

13. Case 53  Clinical: Female, 19 years. Vascular polyp on left side of nose.  PGP 9.5 and CD63 = Positive.  S100, Melan A, SMA, Desmin, EMA, MNF116 = Negative.

18.  Most popular diagnosis…

19.  Neurothekeoma (+/-cellular) 6.77

20. Case 54  Clinical: Female, 28 years old. Slowly growing lesion on chest wall.  Immunohistochemistry: Tumour cells in both components of the tumour are positive for CD34. Negative staining for EMA, Desmin, SMA, S100, FXIIIa, CD31.

26.  Most popular diagnosis…

27.  DFSP with giant cell fibroblastoma areas 5.59

28. Case 55  Clinical: Female, 30 years. Lesion on thigh. ?Haemangioma.

35.  Most popular diagnoses…

36.  Epithelioid haemangioma 4.46  Cutaneous epithelioid angiomatous nodule 1.23  Microvenular haemangioma 0.95

37. Case 56  Clinical: Male, 73 years. Multiple nodules on the buttocks. ?Squamous cell carcinoma.

40.  Most popular diagnosis…

41.  Scabies (+/- Norwegian) 9.80

42. Case 57  Clinical: Male, 63 years. ?BCC.

45.  Most popular diagnosis…

46.  Cutaneous lymphadenoma 8.71

47. Case 58  Clinical: Male, 23 years. Lesion right ring finger.  Special stains: Lesional cells - S100 and EMA positive.

50.  Most popular diagnosis…

51. Neurothekeoma (+/- myxoid)9.72 Neurothekeoma (+/- myxoid)9.72

52. Case 59  Clinical: Male, 87 years. Six month history of itchy dermal nodules.  Special stains: Diffuse positivity for CD79a.  Patchy CD20 and Bcl2 positivity.  CD5 and CD10 negative in this population.  Few aggregates of Bcl6 positive cells. CD23 highlights residual FDC networks only.  Prominent CD3 positive population.  Monotypic expression of Lambda light chains

57.  Most popular diagnosis…

58.  Marginal zone lymphoma 6.16

59. Case 60  Clinical: Female, 75 years. Plaque left shin. ?Lichen simplex.

62.  Most popular diagnosis…

63.  Hypertrophic lichen planus 7.36

64. Case 61  Clinical: Male, 69 years. Forehead lesion. ?Lentigo maligna just above left eyebrow

67.  Most popular diagnosis…

68. Lentigo maligna melanoma Lentigo maligna melanoma

69. Case 62  Female, 61 years old. Lesion excision by plastic surgeon with a diagnosis of verrucous epidermal naevus.

73.  Submitted diagnosis…

74.  Granular parakeratosis

75. Case 63  Female, 38 years. Nodule on the sole of the left foot.  Special stains: Cytokeratin, focally EMA and S100 protein positive.  Negative for SMA, HMB45, p63, CD31 and GFAP.  Approximately 10% of the cells show MIB-1 positivity

80.  Submitted diagnosis…

81.  Benign adnexal tumour

82. Case 64  Male, 79 years old.  Generalised thickening of skin, papular like. ?Scleroderma.  History of monoclonal gammopathy (IgG, Kappa)

85.  Submitted diagnosis…

86. Scleromyxoedema Scleromyxoedema

87. Case 65  female 30 yrs. 2 yr history of cyst neck midline.  EMA++ CD34++

93.  Submitted diagnosis…

94.  Low grade fibromyxoid sarcoma

95. Case 66  Clinical: Female large tumour mass at tip of nose infiltrating septum.  Strongly positive TdT, bcl2, CD99, MNF116, CK20.  Negative for CD3, CD20, CD79a, CD10, bcl6, CD34, S100 and MPO

98.  Submitted diagnosis…

99.  Merkel cell carcinoma

100.  The End