1. Pathology Visions Conference Giri Iyer General Manager, Strategic Development Integrated IT Solutions 10/22/2007 Digital Pathology HCIT Visions – A GE Healthcare Perspective

3. 3 GE Healthcare IITS July 24, 2007 A Tale of Two Cities… Pre-Clinical Research Clinical Care Delivery Patient Safety: Need better Tox data earlier Drug Efficacy: Need better biomarkers and ADME profiles Patient Safety : Five Rights Checking Drug Efficacy: Need better drugs Clinical Trial Process Drug Candidate Funnel weak Drug Costs and Failure Rates  Lost in Translation: Need better data exchange earlier

4. 4 GE Healthcare IITS July 24, 2007 From Quasi-quantitative To Dynamic Range From Single Biomarker To Multiplexing From Dx To enabling Rx To Digital From Glass The Future of Anatomical Pathology

5. 5 GE Healthcare IITS July 24, 2007 Market Adoption Projection Rx adopting first; AMCs for Research only Ref Labs driving clinical; AMCs for Clinical Main stream clinical adoption 2008- 2009 2009- 2010 2010+ Time Market Access Scan times Image Quality Latency FDA approval Workflow Algorithms Workflow ROI story TCO story

6. 6 GE Healthcare IITS July 24, 2007 Key Drivers for Industry Success Whole slide Imaging today.. In vivo molecular imaging tomorrow Better standards for Interoperability…DICOM, Jpeg, HL7, CDISC, MIMIx?, MIAPE? FDA compliance vs speed-to-market trade-offs Better Data Exchange…Fusion between Medical Informatics and Bio Informatics Ultimate litmus test is Drug Efficacy  that is concomitant with Patient Safety

7. 7 GE Healthcare IITS July 24, 2007 GE HCIT Perspective Industry evolution driven through image digitization When its about fast scan times and high resolution images.. GE is a usual suspect Industry definitions changing?  Is it a PACS?  Is it a LIS?  Is it just the old Anatomic Pathology Module on new steroids? Interoperability with existing systems is key to success Customer acceptance will depend upon transforming Pathology workflow with significant value added Thanks for having us here.. The youngest start-up in the market… much to learn