1. Chapter 3 Mortality in End Stage Kidney Disease 2014 ANZDATA Registry 37th Annual Report Data to 31-Dec-2013

2. 2014 ANZDATA Registry 37 th Annual Report

4. Survival (95% CI) among People who Commenced Renal Replacement Therapy 2004-2013 Age at RRT startYearsAustraliaNew Zealand 0-24197 (96, 98)97 (93, 99) 295 (93, 97)94 (90, 97) 592 (89, 94)91 (85, 94) 25-44196 (96, 97)97 (95, 98) 292 (91, 93)92 (89, 94) 585 (84, 86)75 (71, 79) 45-64192 (92, 93)92 (91, 93) 285 (85, 86)84 (82, 85) 568 (67, 69)58 (55, 60) 65-74186 (85, 87)87 (85, 89) 275 (74, 76)74 (71, 77) 545 (43, 46)36 (33, 40) 75-84181 (80, 82)78 (74, 82) 266 (64, 67)58 (53, 63) 530 (28, 32)22 (17, 27) 85+170 (66, 74)76 (58, 87) 252 (48, 57)48 (30, 63) 520 (16, 25)11 (3, 27)

5. 2014 ANZDATA Registry 37 th Annual Report Survival (95% CI) among People who Commenced Dialysis 2004-2013 (Non-indigenous) Age at RRT startYearsAustraliaNew Zealand 0-24197 (95, 98)96 (89, 98) 293 (90, 96)94 (85, 97) 588 (81, 92)82 (62, 92) 25-44197 (96, 98)98 (96, 99) 292 (90, 93)91 (86, 94) 581 (78, 83)73 (64, 80) 45-64192 (91, 93)91 (89, 93) 285 (84, 86)82 (79, 84) 562 (60, 64)56 (52, 61) 65-74186 (85, 87)86 (83, 89) 275 (73, 76)74 (70, 77) 544 (42, 45)35 (30, 39) 75-84181 (80, 82)76 (72, 81) 266 (64, 67)57 (51, 62) 530 (28, 32)20 (15, 26) 85+170 (66, 74)75 (56, 86) 252 (48, 57)49 (30, 65) 521 (16, 25)12 (3, 28)

6. 2014 ANZDATA Registry 37 th Annual Report Death Rates per 100 patient-years during Renal Replacement Therapy - 2013 CategoryLevel Dialysis rate 95% CI Transplan t rate 95% CI Country Australia13.112.513.82.32.02.6 New Zealand13.712.315.21.91.32.7 Age <253.51.76.50.50.11.6 25-444.03.15.10.80.51.2 45-649.99.110.81.91.62.3 65-8417.816.718.85.44.46.5 85+34.529.440.239.58.1115.4 Diabetes status Non-diabetic11.310.512.11.91.62.2 Type 1 diabetes13.710.417.63.61.96.1 Type 2 diabetes15.514.516.53.42.64.2 Coronary disease No8.57.99.21.61.31.8 Yes18.517.519.64.83.95.7 Race Non Indigenous (AUS) 13.412.714.12.32.02.6 Non Indigenous (NZ)15.313.117.81.91.22.8 Aboriginal/TSI12.310.614.34.52.18.6 Māori (AUS)14.88.623.71.90.010.9 Māori (NZ)13.611.216.42.70.77.0 Pacific (AUS)9.16.113.21.30.07.1 Pacific (NZ)10.88.413.80.0 4.1

7. 2014 ANZDATA Registry 37 th Annual Report

11. Median Survival on Dialysis by Age CountryAge at startMedian (25th and 75th centiles), years Australia 0-24. (8.1,.) 25-449.8 (5.4,.) 45-646.6 (3.2,.) 65-744.3 (2.0, 7.8) 75-843.2 (1.4, 5.6) 85+2.1 (0.7, 4.1) New Zealand 0-248.6 (8.2, 0) 25-447.5 (4.2, 0) 45-645.4 (2.8, 0) 65-743.7 (1.9, 5.9) 75-842.6 (1.1, 4.6) 85+1.9 (1.0, 3.1)

12. 2014 ANZDATA Registry 37 th Annual Report Survival on Dialysis by Age and Comorbidity amongst Older People Years (median, 25th and 75th centiles) Age at startAny vascular diseaseDiabetesAustraliaNew Zealand 65-69No 6.1 (3.3,.)5.0 (2.7, 7.1) 65-69NoYes5.1 (3.1,.)5.0 (3.0, 6.8) 65-69YesNo4.3 (1.7, 7.6)4.0 (1.9, 5.8) 65-69Yes 4.0 (2.0, 7.1)3.0 (1.6, 4.6) 70-74No 5.4 (2.5,.)4.4 (1.9, 6.3) 70-74NoYes5.4 (2.7,.)4.1 (2.2, 6.9) 70-74YesNo3.8 (1.6, 6.9)3.0 (1.6, 4.7) 70-74Yes 3.1 (1.5, 5.5)3.2 (1.5, 4.9) 75-79No 4.8 (2.1, 7.4)3.6 (1.7, 6.2) 75-79NoYes4.2 (2.1, 6.5)4.3 (1.7, 5.8) 75-79YesNo3.1 (1.4, 5.8)1.9 (0.6, 3.7) 75-79Yes 2.9 (1.3, 5.3)1.9 (0.8, 4.4) 80-84No 3.4 (1.8, 6.1)2.7 (1.5, 4.4) 80-84NoYes3.1 (1.8, 4.6)3.8 (1.2, 6.0) 80-84YesNo2.5 (1.1, 4.8)2.1 (1.2, 4.1) 80-84Yes 2.4 (1.0, 4.4)3.1 (2.0, 4.9) 85+No 3.1 (1.2, 5.5)2.4 (1.0, 3.6) 85+NoYes2.4 (1.4, 7.9)0.9 (0.9, 0.9) 85+YesNo2.0 (0.7, 3.9)1.9 (1.0, 3.1) 85+Yes 1.5 (0.4, 3.3)1.7 (1.2,.)

13. 2014 ANZDATA Registry 37 th Annual Report

17. Modality and Age at time of Death - 2013 Cause of death HaemodialysisPeritoneal DialysisGraft 0-4445-6465-7475+Total0-4445-6465-7475+Total0-4445-6465-7475+Total Cardiovascular1912696161402115 2657516211355 Withdrawal985122258474116264083272718 Cancer12018125101451053319562 Infection3301839903810133421615538 Other1389848026641216195151821852 Australia4535033855012839527110323519907838225 Cardiovascular9432518952181794606208 Withdrawal21116 45361342601012 Cancer031150011214319 Infection3161283918521613105 Other21318841171272713217 New Zealand1686725122573948231173178331

18. 2014 ANZDATA Registry 37 th Annual Report Reason for Withdrawal from Renal Replacement Therapy - 2013 CountryReason for withdrawalHDPDGraft Australia Psychosocial171288 Refused further treatment1020 Suicide502 Cardiovascular co-morbidity94123 Cerebrovascular co-morbidity36112 Peripheral vascular co-morbidity50131 Malignancy90142 Dialysis access difficulties1830 New Zealand Psychosocial20100 Refused further treatment011 Suicide000 Cardiovascular co-morbidity620 Cerebrovascular co-morbidity250 Peripheral vascular co-morbidity740 Malignancy921 Dialysis access difficulties120

19. 2014 ANZDATA Registry 37 th Annual Report Time from Renal Replacement Therapy Start to Death, in Patients who Withdrew and Died in 2013 Time from first RRT (years) AustraliaNew Zealand 0-4445-6465-7475+Total0-4445-6465-7475+Total 0221244289136111 1115182963233210 2534551011951510 26 5438531332281710826 Total12108150305575518292173