1. Genotype/Phenotype Probability Phenotype= The observable characteristic of an organism (Expression of genes) -Ratios- 1 X H X H: 1 X H X h: 1 X H Y : 1 X h Y - Percentages- 25% With Hemophilia 75% Without Hemophilia Genotype- The specific Allele makeup of an organism - Ratios- 1 X H X H: 1 X H X h: 1 X H Y : 1 X h Y - Percentages- 25% X H X H: 25% X H X h: 25% X H Y : 25% X h Y Punnet square of a Normal Male and a Carrier Female XHXH Y XHXH XhXh XHXHXHXH XHYXHY XHXhXHXh XhYXhY

2. Student Practice Now you try! Genotype: Ratio: 2 HY: 2 hY Percentage: 50% Green 50% Blue Phenotype: Ratio: 2 HY: 2 hY Percentage: 50% HY 50% hY H h Y HY hYhY hYhY For example: Eye color

3. Three generation X-Linked Pedigree Chart White= Person is fine. May of two “healthy genes.” Black= Person is affected. Has 2 “bad” genes. How to read: Circle= Female Square= Male Shaded Circle= Female Hemophilia Carrier Shaded Square= Male hemophiliac

4. Student Practice: How to read an X- Linked Pedigree Chart. Key: Square= Male Circle= Female Red Square= Male hemophiliac Yellow Circle= Female carrier Joe Jan Tom Marc Cindy Kayla Dan Tom Jr. Lisa You think you know X- linked Pedigree’s? If so: 1.Who is the main source of the hemophilia in this family? 2.How many people in this chart DO NOT have any form of hemophilia? 3.If Marc were to have children with a normal female, what are the odds of one of them having some form of hemophilia?