1. Unit 6 Seminar Chapter 10 HS 200: Diseases of the Human Body Dr. Allan Ayella

2. Unit 6 Agenda Over-view of Unit 5 Unit 6 Expectations Seminar discussion Questions and Answer

3. Any issues that you came across in Unit 5 that I need to address? Over-view of Unit 5

4. Unit 6 Expectations

7. Background Information Pg 439

8. Circulatory system What is the primary function of the circulatory system? What are the components of the vascular system? Pg 93

9. The primary function of the circulatory system is to nourish the visceral with nutrients and oxygen The components of the vascular circuit include the lungs (pulmonary), the peripheral vessels (mainly iliac vessels), the visceral organs (digestive and urinary system) and the cephalic

10. Coronary Artery Disease Description of CAD? Pg 441

11. CAD Pg 441 Coronary artery disease: A condition involving the arteries that supply the myocardium, in which the arteries become narrowed due to atherosclerotic deposits over time, causing temporary cardiac ischemia and eventually heart attack

12. Etiology of CAD Difference btn atheroma vs. thrombus? Pg 80

13. Etiology of CAD Atheroma- mass of fibro-fatty material, cells and lipids Pg 80 Thrombus- A blood clot attached to the interior wall of the blood vessel, often causing vascular obstruction

14. Etiology of CAD A combination of the endothelial damage and the atheroma is called a ______________ Pg 80

15. Etiology of CAD A combination of the endothelial damage and the atheroma is called a Plaque Pg 442

16. Etiology of CAD List the consequences of atherosclerosis in different tissues Pg 78

17. Etiology of CAD List the consequences of atherosclerosis - Heart: Partial occlusion Angina pectoris Total occlusion MI Pg 443 - Brain: Partial occlusion Ischemic attack Total occlusion CVA - Vessels: Aorta Aneurysm LegsPVD (Gangrene and amputation)

19. Sites of MI State the sites of MI in men Pg 448

20. Sites of MI Pg 448

21. Diagnosis of MI b) How is MI diagnosed? Pg 447 a) Are the MI sites the same in men and in women?

22. Diagnosis of MI Thorough medical history Electrocardiogram changes Chest radiographic films Changes in enzyme levels e.g. CPK, LDH, AST, Pg 447

23. Patient education of MI State patient education is used in MI? Pg 447

24. Patient education of MI State patient education is used in MI? - Call 9ll for emergency - Chew 325g aspirin tablets - Defibrillation where possible Pg 447

25. Treatment of MI Pg 450 What is the time window from the onset of the infarction before permanent damage results?

26. Treatment of MI Pg 450 What is the time window from the onset of the infarction before permanent damage results? Six hours

27. Cardiac arrest ___________ __ is a sudden, unexpected cessation of cardiac activity Pg 79

28. Cardiac arrest _Cardiac arrest is a sudden, unexpected cessation of cardiac activity Pg 79

29. Cardiac arrest What measures are initiated to reverse a cardiac arrest? Pg 79

30. Cardiac arrest What measures are initiated to reverse a cardiac arrest? CPR must be instituted within 4 to 6 minutes of cardiac arrest by a trained, advanced life-support personnel. Cardiac drugs including adrenaline, dobutamine and antiarrhythmic drugs must be administered. In addition, therapeutic hypothermia can be tried Pg 79

31. Hypertension Describe the types of hypertension Pg 25

32. Hypertension Pg 25 What is the first indication of hypertension?

33. Hypertension Pg 25 What is the first indication of hypertension? Elevated blood pressure readings -- systolic reading greater than 140 mm Hg and diastolic reading greater than 90 mm Hg indicate hypertension

34. Hypertension Discuss the treatment of hypertension Pg 452

35. Hypertension Discuss the treatment of hypertension Diuretics to reduce circulating blood volume Beta-adrenergic blockers to slow heartbeat Vasodilators to dilate vessels Angiotensin-converting enzyme (ACE) inhibitors to produce vasodilation and increase renal blood flow

36. What disease is characterized by the following symptoms? Pg 454