1.  Detection of metachronous tumors  Recognition of local recurrence Follow-up Flexible endocsopy

2. Benefits of colonoscopic surveillance after curative resection of CRC  290 patients, median time of follow-up, 20m  Follow-up colonoscopies recommended at 6-month or 1-year intervals  31 (10.7%) of patients were diagnosed subsequently with intraluminal recurrence  21(67,7%) of recurrences occurred within 2 years  45.2% (14p) of the recurrences were intraluminal  38.7% (17p) were asymptomatic at the time of the detection 1967-1991 Columbia-Presbyterian Medical Centre, New York E. Lautenbach, Ann Surg 1994.

3.  Metachronous neoplasms occur in 2,1% with median time of the diagnosis 128 months  In 66,7% of the diagnosed recurrences, asymptomatic  In 88,3% of patients, no curative second-look surgery  The rate of discovered metachronous tumors was similar, irrespective of the follow-up regimen Follow-up Benefits of colonoscopic surveillance after curative resection of CRC E. Lautenbach, Ann Surg 1994.

4. Resectability of LR  75% of curative resections in patients with asymptomatic LR  15,8% of curative resections in patients with symptomatic LR Conclusion  Earlier diagnosis of the recurrence may increase likelihood of the cure  Aggressive colonoscopic surveillance in the first two years E. Lautenbach, Ann Surg 1994. Benefits of colonoscopic surveillance after curative resection of CRC