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29 Sep – 1 Oct, 2014 AAI-7@Jakarta, Indonesia 1 Step-by-step guidance for calculating AAMR Department of Environmental Epidemiology, University of Occupational and Environmental Health, Japan
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Contents 2 How to DOWNLOAD and COMPILE the necessary data Mortality Database Population Database How to calculate the AAMR
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Exercise for today is: Calculation of AAMR of Mesothelioma in Japan, 2000-2011 3 Data on Mesothelioma death in Japan during 2000-2011 (by age group) Population of Japan during 2000-2011 (by age group) Software: Microsoft Excel Necessary data:
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Mortality Database 4 How to DOWNLOAD the necessary data
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5 How to download the necessary data: Mortality database Available (downloadable) from WHO website: http://www.who.int/healthinfo/statistics/mortality_rawdata/en/
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6 Click here How to download the necessary data: Mortality database Available (downloadable) from WHO website: http://www.who.int/healthinfo/statistics/mortality_rawdata/en/index.html http://www.who.int/healthinfo/statistics/mortality_rawdata/en/index.html (Last updated: 25 Feb 2014)
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7 International Classification of Diseases, 10 th Revision (ICD-10) Mesothelioma C45Mesothelioma C450 Mesothelioma of pleura C451 Mesothelioma of peritoneum C452 Mesothelioma of pericardium C457 Mesothelioma of other sites C459 Mesothelioma, unspecified Data available for the period: 1994-2011 How to download the necessary data: Mortality database
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8 CountryYearSexCauseDeath1Death2Death3…..Death26 316019951C45020100…0 316019952C4507400…0 ………… …………… 316020001C45036700…0 316020002C4508900…0 316020001C4513000…0 316020002C4512400…0 3160 ……… …………… 3160 – Country code for Japan Sex: 1=Male; 2=Female Death1: Total number of deaths Death2 – Death25 - The number of deaths in each age group D2=Death at age 0 year, D3=age 1; D4=age 2; …; D25=age 95+; D26=Deaths at age unspecified (Explanation is available in Documentation file in WHO website) Note: The format of age group differs by country and year How to download the necessary data: Mortality database
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Population Database 9 How to DOWNLOAD the necessary data
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10 Data are available in WHO Website : http://www.who.int/healthinfo/statistics/mortality_rawdata/en/ (Last updated: 25 Feb 2014) Click here How to download the necessary data: Population database
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11 CountryYearSexPop1Pop2Pop3…..Pop26 31601950140811800 11822001286500 316019502 4238790011338001236100 ……… 316020001 61488005596408592634 316020002 64124628566458564570 316020011 61595000599000593000 316020012 64313000567000563000 3160 …… …………… 3160 – Country code for Japan Sex: 1=Male; 2=Female Pop1: Population at all ages Pop2 – Pop25 – Population at each age group Pop2=Pop at age 0 year, Pop3=age 1; Pop4=age 2; …; Pop25=age 95+; Pop26=Pop at age unspecified (Explanation is available in Documentation file in WHO website) How to download the necessary data: Population database
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12 -, Data are not available Format - general mortality reporting Format number 00010203040506070809 YearsAll ages 0000000000 1111-41 2222N 3333O 4444 55-9 5-14 A 1010-14 G 1515-19 15-24 E 2020-24 2525-29 25-34 D 3030-34 I 3535-39 35-44 S 4040-44 T 4545-49 45-54 R 5050-54 I 5555-59 55-64 B 6060-64 U 6565-69 65 &+65-7465 &+T 7070-74 70 &+I 7575-79 75 &+ O 8080-84 N 8585-8985 &+ 9090-94 9595 &+ Unknown
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13 How to DOWNLOAD the necessary data Mortality Database Population Database How to COMPILE data Mortality Database Population Database How to calculate AAMR
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14 How to COMPILE data
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To COMPILE data 15 Mortality Database Combine data using same format of age-group. Combine number of deaths for different anatomical sites and sexes in the same reported year. Population Database Combine data using same format of age-group and combine both sexes.
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16 YearCauseSex Death1D2D6D21D25 2000C4501 3670 … 0 … 50 … 4 2000C4502 890 … 0 … 15 … 0 2000C4511 300 … 0 … 5 … 0 2000C4512 240 … 0 … 3 … 0 2000C4521 30 … 0 … 0 … 0 2000C4522 10 … 0 … 0 … 0 2000C4571 40 … 0 … 0 … 0 2000C4572 110 … 0 … 2 … 0 2000C4591 1260 … 0 … 20 … 0 2000C459 2 550 … 0 … 11 … 1 Combine age-groups into one, respectively Combine anatomical sites and sexes Combine sexes How to COMPILE the necessary data: Mortality database Death 0-4 Death 75+
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Mesothelioma Mortality Data of Japan (2000-2011) 17 Year Deaths 0-4 Deaths 5-9 Deaths 10-14 …Deaths 70-74 Deaths 75+ Unspecif ied Deaths Total 2000000 … 1292410710 2001000 … 1152650772 2002000 … 1202980810 2003000 … 1313270878 2004010 … 1653540953 2005000 … 1533590911 2006000 … 17042101050 2007000 … 15444801068 2008000 … 18846701170 2009000 … 20849301156 201001020052801209 201100021958301258 (C45, Both sex, 2000-2011) How to COMPILE the necessary data: Mortality database
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18 YearSex Pop1Pop2 … Pop6Pop21 … Pop25 20001 61,488,005596,408 … 602,8421,621,115 … … 20002 64,124,628566,458 … 573,5602,518,452 … … 20011 61,595,000599,000 … 604,0001,776,000 … … 20012 64,313,000567,000 … 577,0002,638,000 … … 20021 61,591,000594,000 … 608,0001,921,000 … … 20022 64,417,000563,000 … 579,0002,735,000 … … …… …… … …… … … …… …… … …… … … 20111 61,453,000544,000 … 543,0002,670,000 … 65,000 2011 2 64,727,000516,000 … 517,0003,452,000 … 298,000 Combine age-groups into one, respectively Combine sexes How to COMPILE the necessary data: Population database Pop 0-4 Pop 75+
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Population Data of Japan (2000-2011) 19 Year Pop 0-4 Pop 5-9 Pop 10-14 …Pop 70-74 Pop 75+ Unspecifi ed 2000 5,859,9735,984,8296,507,152 … 5,889,9988,979,838 0 2001 5,844,0005,952,0006,333,000 … 6,039,0009,499,000 0 2002 5,819,0005,935,0006,197,000 … 6,190,00010,008,000 0 2003 5,743,0005,936,0006,073,000 … 6,338,00010,511,000 0 2004 5,680,0005,889,0006,015,000 … 6,444,00011,033,000 0 2005 5,547,3955,899,5625,990,607 … 6,634,85011,596,534 0 2006 5,449,0005,872,0005,961,000 … 6,786,00012,120,000 0 2007 5,380,0005,823,0005,936,000 … 6,893,00012,657,000 0 2008 5,347,0005,736,0005,935,000 … 6,927,00013,172,000 0 2009 5,323,0005,639,0005,902,000 … 6,879,00013,662,000 0 2010 5,254,4615,550,0075,884,2756,987,39114,149,539 0 2011 5,256,0005,446,0005,865,0007,151,00014,662,000 0 (Population, Both sex, 2000-2011) How to COMPILE the necessary data: Population database
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20 How to DOWNLOAD the necessary data Mortality Database Population Database How to COMPILE data Mortality Database Population Database How to calculate AAMR
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Calculation of AAMR (per million person) due to Mesothelioma in Japan, 2000 16-18 October, 2013 21 Age group Death Pop 0-40 5,859,973 5-905,984,829 10-140 6,507,152 … … 65-69100 7,091,585 70-741295,889,998 75+2418,979,838 How to calculate AAMR 1.Calculate the Age-specific mortality rate 2.Adjust with standard population
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22 Age group Death Pop 1,000,000 Age specific crude mortality rate 0-405,859,973 0 5-905,984,829 0 10-140 ÷ 6,507,152 x = 0 … … … … 65-691007,091,58514.101 70-741295,889,99821.902 75+2418,979,83826.838 How to calculate AAMR 1.Calculate the ASMR Calculation of AAMR (per million person) due to Mesothelioma in Japan, 2000
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Standard population 23 Age Group Doll et al. World Standard Scandinavian ("European" ) standard WHO World Standard* (World 1966)(World 2000) 0-412.00 8.008.86 5-910.00 7.008.69 10-149.00 7.008.6 15-199.00 7.008.47 20-248.00 7.008.22 25-298.00 7.007.93 30-346.00 7.007.61 35-396.00 7.007.15 40-446.00 7.006.59 45-496.00 7.006.04 50-545.00 7.005.37 55-594.00 6.004.55 60-644.00 5.003.72 65-693.00 4.002.96 70-742.00 3.002.21 75-791.00 2.001.52 80-840.50 1.000.91 85+0.50 1.000.63 All Ages100.00 * For purposes of comparison, the WHO Standard age group 85+ is an aggregate of the age groups 85-89, 90-94, 95-99 Source: Age Standardization of Rates: A New WHO Standard, GPE Discussion Paper Series: No. 31, EIG/GPE/EBD, World Health Organization. How to calculate AAMR
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Calculation of AAMR (per million person) due to Mesothelioma in Japan, 2000 24 Age groupDeath Pop 10 6 ASMR Age distribution of SP AAMR 0-405,859,973 0 0.0886 0 5-905,984,829 0 0.0869 0 10-140 ÷ 6,507,152 x = 0x 0.086 =0 … … … … 65-691007,091,58514.101 0.0296 0.417 70-741295,889,99821.902 0.0221 0.484 75+2418,979,83826.8380.03060.813 AAMR in year 2000 = Sum of AAMR of each age group Sum 3.016 How to calculate AAMR Apply same method for each year from 2001to 2011 2. Adjust with standard population
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AAMR of Mesothelioma in Japan during 2000-2011 16-18 October, 2013 WHO-Europe Workshop@Bonn, Germany 25 Finding
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26 The number of the report years12 Number of deaths11,945 AAMR (by year) 20003.016 20013.223 20023.265 20033.453 20043.617 20053.362 20063.763 20073.724 20083.974 20093.806 20103.854 20113.858 AAMR for Mesothelioma, 2000-2010, Japan (Per million persons/year) 3.576131 AAI-7@Jakarta, Indonesia 29 Sep – 1 Oct, 2014 AAMR of Mesothelioma in Japan during 2000-2011 (per million persons/year)
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27 THANK YOU FOR YOUR ATTENTION AAI-7@Jakarta, Indonesia 29 Sep – 1 Oct, 2014
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