1. Fig S1. miR-10b overexpression in exosomes derived from MDA-MB-231 cells stably expressing miR-10b as compared to vector control exosomes. Supplementary information Fig. S1 

2. miRNAFold changeSEM hsa-let-7a1.590.21 hsa-miR-1 3.371.23 hsa-miR-170.810.17 hsa-miR-221.600.25 hsa-miR-29a2.140.55 hsa-miR-32 1.960.01 hsa-let-7b0.990.14 hsa-miR-7 0.550.06 hsa-miR-18a0.720.11 hsa-miR-23a1.020.08 hsa-miR-29b 2.600.23 hsa-miR-34a2.380.33 hsa-let-7c1.500.24 hsa-miR-9 1.570.26 hsa-miR-18b0.680.12 hsa-miR-23b0.960.15 hsa-miR-29c2.170.18 hsa-miR-34b0.380.09 hsa-let-7d1.690.23 hsa-miR-10a9.531.47 hsa-miR-19a0.830.11 hsa-miR-24 0.800.11 hsa-miR-30a1.720.20 hsa-miR-34c-5p0.530.01 hsa-let-7e1.640.21 hsa-miR-10b13.211.51 hsa-miR-19b 0.970.15 hsa-miR-251.640.23 hsa-miR-30b1.210.21 hsa-miR-92a 0.850.06 hsa-let-7f1.470.22 hsa-miR-15a1.560.23 hsa-miR-20a 0.850.15 hsa-miR-26a 1.270.23 hsa-miR-30c 2.100.23 hsa-miR-92b0.590.15 hsa-let-7g1.350.14 hsa-miR-15b1.040.14 hsa-miR-20b0.750.08 hsa-miR-26b1.120.22 hsa-miR-30e1.850.31 hsa-miR-96 0.810.13 hsa-let-7i2.560.17 hsa-miR-16 1.160.07 hsa-miR-211.870.17 hsa-miR-27b 1.140.02 hsa-miR-31 0.53 hsa-miR-98 1.440.50 miRNAFold changeSEM hsa-miR-99a9.090.75 hsa-miR-100 7.413.75 hsa-miR-1011.040.09 hsa-miR-1031.160.26 hsa-miR-106a0.780.10 hsa-miR-106b 1.760.13 hsa-miR-1071.120.10 hsa-miR-122 1.100.21 hsa-miR-1240.550.08 hsa-miR-125a-5p1.430.30 hsa-miR-125b 4.560.33 hsa-miR-1265.041.20 hsa-miR-126*3.950.61 hsa-miR-127-5p 0.720.22 hsa-miR-1280.920.09 hsa-miR-129-5p0.48 hsa-miR-130a1.130.11 hsa-miR-133a1.320.11 hsa-miR-133b1.050.26 hsa-miR-1344.550.66 hsa-miR-135a0.280.05 hsa-miR-135b 0.240.04 hsa-miR-1360.110.05 hsa-miR-1372.450.40 hsa-miR-1384.260.77 hsa-miR-140-5p3.350.48 hsa-miR-141 0.00 hsa-miR-142-5p4.430.57 hsa-miR-142-3p9.040.41 hsa-miR-143 0.840.08 hsa-miR-1444.041.58 hsa-miR-1451.110.08 hsa-miR-146a 2.040.92 hsa-miR-146b-5p 5.701.32 hsa-miR-148a 0.540.08 hsa-miR-148b0.620.07 hsa-miR-1490.900.16 hsa-miR-1500.480.03 hsa-miR-151-5p1.030.13 hsa-miR-1532.050.59 hsa-miR-1540.070.01 hsa-miR-155 0.030.01 hsa-miR-181a2.090.27 hsa-miR-181b 2.490.28 hsa-miR-181c2.450.30 hsa-miR-181d 2.610.40 hsa-miR-182 0.670.05 hsa-miR-183 1.010.01 miRNAFold changeSEM hsa-miR-1841.550.42 hsa-miR-1850.890.22 hsa-miR-1860.930.12 hsa-miR-188-5p0.550.08 hsa-miR-1901.530.47 hsa-miR-1911.370.17 hsa-miR-1922.850.51 hsa-miR-193a-5p1.430.24 hsa-miR-193b0.180.02 hsa-miR-194 1.910.37 hsa-miR-1951.160.14 hsa-miR-196a 0.140.00 hsa-miR-196b0.430.13 hsa-miR-199a-5p 1.770.42 hsa-miR-199a-3p 0.620.24 hsa-miR-199b-5p0.700.22 hsa-miR-200a1.960.36 hsa-miR-200b1.150.22 hsa-miR-200c0.020.00 hsa-miR-2021.450.20 hsa-miR-2030.00 hsa-miR-2044.730.92 hsa-miR-2050.00 hsa-miR-2060.760.03 hsa-miR-2101.680.21 hsa-miR-2121.840.32 hsa-miR-2140.880.06 hsa-miR-2151.470.19 hsa-miR-216a1.430.19 hsa-miR-218 12.681.44 hsa-miR-219-5p 0.820.13 hsa-miR-220a3.851.25 hsa-miR-2214.973.60 hsa-miR-2223.762.14 hsa-miR-2230.170.16 hsa-miR-2242.700.76 hsa-miR-328 0.600.22 hsa-miR-296-5p0.430.33 hsa-miR-301a1.891.25 hsa-miR-3354.101.21 hsa-miR-342-5p0.350.11 hsa-miR-3635.350.11 hsa-miR-3721.200.29 hsa-miR-3731.250.41 hsa-miR-3750.750.15 hsa-miR-376a 0.00 hsa-miR-3780.410.07 hsa-miR-3800.810.25 Table S1.Endogenous level of miRNA expression in MDA-MB-231 cells as compared to HMLE cells

3. Table S2. Secretory miRNA expression in MDA-MB-231 supernatant as compared to HMLE supernatant miRNAFold changeSEM hsa-let-7a1.000.62 hsa-miR-1 1.380.79 hsa-miR-170.600.16 hsa-miR-221.050.56 hsa-miR-29a2.581.51 hsa-miR-32 5.002.83 hsa-let-7b0.880.30 hsa-miR-7 1.630.08 hsa-miR-18a1.700.81 hsa-miR-23a0.740.14 hsa-miR-29b 1.000.12 hsa-miR-34a3.252.94 hsa-let-7c0.600.14 hsa-miR-9 1.09 hsa-miR-18b2.182.17 hsa-miR-23b1.411.02 hsa-miR-29c0.750.06 hsa-miR-34b0.890.00 hsa-let-7d1.210.33 hsa-miR-10a2.750.59 hsa-miR-19a1.370.40 hsa-miR-24 0.640.39 hsa-miR-30a0.460.30 hsa-miR-34c-5p1.500.67 hsa-let-7e4.131.93 hsa-miR-10b5.020.48 hsa-miR-19b 0.910.38 hsa-miR-251.981.46 hsa-miR-30b1.350.59 hsa-miR-92a 1.070.81 hsa-let-7f2.231.23 hsa-miR-15a1.390.51 hsa-miR-20a 1.030.45 hsa-miR-26a 0.390.13 hsa-miR-30c 4.962.45 hsa-miR-92b1.891.02 hsa-let-7g1.360.90 hsa-miR-15b1.060.28 hsa-miR-20b0.680.20 hsa-miR-26b1.810.81 hsa-miR-30e0.980.09 hsa-miR-96 1.790.38 hsa-let-7i1.340.34 hsa-miR-16 0.940.06 hsa-miR-210.920.50 hsa-miR-27b 2.131.33 hsa-miR-31 0.450.43 hsa-miR-98 1.980.98 miRNAFold changeSEM hsa-miR-99a2.881.65 hsa-miR-100 1.950.11 hsa-miR-1010.22 hsa-miR-1030.460.30 hsa-miR-106a0.220.01 hsa-miR-106b 2.920.40 hsa-miR-1070.30 hsa-miR-122 0.680.12 hsa-miR-1242.220.73 hsa-miR-125a-5p0.520.13 hsa-miR-125b 1.060.35 hsa-miR-1261.000.00 hsa-miR-126*0.680.12 hsa-miR-127-5p 0.780.22 hsa-miR-1280.380.18 hsa-miR-129-5p1.140.32 hsa-miR-130a4.214.07 hsa-miR-133a1.581.02 hsa-miR-133b0.50 hsa-miR-1345.66 hsa-miR-135a0.750.01 hsa-miR-135b 0.800.03 hsa-miR-1360.780.22 hsa-miR-1370.510.49 hsa-miR-1384.290.03 hsa-miR-140-5p0.960.71 hsa-miR-141 1.180.01 hsa-miR-142-5p0.680.12 hsa-miR-142-3p0.680.12 hsa-miR-143 0.290.27 hsa-miR-1440.40 hsa-miR-1450.780.22 hsa-miR-146a 1.10 hsa-miR-146b-5p 0.00 hsa-miR-148a 1.000.00 hsa-miR-148b7.716.71 hsa-miR-1491.21 hsa-miR-1502.11 hsa-miR-151-5p1.000.00 hsa-miR-1530.870.13 hsa-miR-1540.13 hsa-miR-155 0.50 hsa-miR-181a0.290.14 hsa-miR-181b 0.880.48 hsa-miR-181c0.470.08 hsa-miR-181d 0.380.06 hsa-miR-182 0.780.22 hsa-miR-183 2.891.89 Fold changeSEM hsa-miR-1840.670.11 hsa-miR-1850.590.41 hsa-miR-1860.630.15 hsa-miR-188-5p1.431.10 hsa-miR-1900.670.11 hsa-miR-1910.540.22 hsa-miR-1920.50 hsa-miR-193a-5p1.530.83 hsa-miR-193b0.910.80 hsa-miR-194 0.28 hsa-miR-1950.190.04 hsa-miR-196a 0.990.42 hsa-miR-196b2.710.65 hsa-miR-199a-5p 0.670.11 hsa-miR-199a-3p 0.670.11 hsa-miR-199b-5p0.28 hsa-miR-200a0.430.13 hsa-miR-200b0.510.26 hsa-miR-200c0.530.47 hsa-miR-2020.650.35 hsa-miR-2030.390.10 hsa-miR-2040.890.11 hsa-miR-2050.00270.002 hsa-miR-2062.340.34 hsa-miR-2100.670.45 hsa-miR-2122.901.21 hsa-miR-2140.640.27 hsa-miR-2150.890.11 hsa-miR-216a0.470.22 hsa-miR-218 0.890.11 hsa-miR-219-5p 0.28 hsa-miR-220a0.890.11 hsa-miR-2210.690.52 hsa-miR-2221.240.88 hsa-miR-2230.50 hsa-miR-2240.760.24 hsa-miR-328 1.991.59 hsa-miR-296-5p0.400.37 hsa-miR-301a0.890.11 hsa-miR-3350.28 hsa-miR-342-5p0.780.22 hsa-miR-3630.670.11 hsa-miR-3720.740.35 hsa-miR-3730.670.11 hsa-miR-3750.660.16 hsa-miR-376a 0.890.11 hsa-miR-3780.31 hsa-miR-3801.290.29