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This article and any supplementary material should be cited as follows: Sandroff BM, Hubbard MS, Pilutti LA, Motl RW. No association between body composition.

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Presentation on theme: "This article and any supplementary material should be cited as follows: Sandroff BM, Hubbard MS, Pilutti LA, Motl RW. No association between body composition."— Presentation transcript:

1 This article and any supplementary material should be cited as follows: Sandroff BM, Hubbard MS, Pilutti LA, Motl RW. No association between body composition and cognition in ambulatory persons with multiple sclerosis: A brief report. J Rehabil Res Dev. 2015;52(3):XX-XX. http://dx.doi.org/10.1682/JRRD.2014.09.0208 Slideshow Project DOI:10.1682/JRRD.2014.09.0208JSP No association between body composition and cognition in ambulatory persons with multiple sclerosis: A brief report Brian M. Sandroff, MS; Elizabeth A. Hubbard, MS; Lara A. Pilutti, PhD; Robert W. Motl, PhD

2 This article and any supplementary material should be cited as follows: Sandroff BM, Hubbard MS, Pilutti LA, Motl RW. No association between body composition and cognition in ambulatory persons with multiple sclerosis: A brief report. J Rehabil Res Dev. 2015;52(3):XX-XX. http://dx.doi.org/10.1682/JRRD.2014.09.0208 Slideshow Project DOI:10.1682/JRRD.2014.09.0208JSP Aim – Investigate the associations between measures of body composition and domains of cognitive function in ambulatory persons with multiple sclerosis (MS). Relevance – Evidence suggests body fat is inversely associated with cognitive functioning. – This association might further be augmented in presence of immune-mediated, inflammatory disease such as MS.

3 This article and any supplementary material should be cited as follows: Sandroff BM, Hubbard MS, Pilutti LA, Motl RW. No association between body composition and cognition in ambulatory persons with multiple sclerosis: A brief report. J Rehabil Res Dev. 2015;52(3):XX-XX. http://dx.doi.org/10.1682/JRRD.2014.09.0208 Slideshow Project DOI:10.1682/JRRD.2014.09.0208JSP Method Cross-sectional study investigating associations between objective measures of body composition and cognitive function in 60 persons with MS. Following tests performed : – Neurological examination for Expanded Disability Status Scale scores. – Brief International Cognitive Assessment in Multiple Sclerosis neuropsychological battery for measurement of cognitive processing speed, verbal learning and memory, and visual learning and memory. – Whole-body fat mass, percent body fat, lean body mass, and bone mineral density measured using dual-energy X-ray absorptiometry.

4 This article and any supplementary material should be cited as follows: Sandroff BM, Hubbard MS, Pilutti LA, Motl RW. No association between body composition and cognition in ambulatory persons with multiple sclerosis: A brief report. J Rehabil Res Dev. 2015;52(3):XX-XX. http://dx.doi.org/10.1682/JRRD.2014.09.0208 Slideshow Project DOI:10.1682/JRRD.2014.09.0208JSP Results Whole-body fat mass and percent body fat not associated with any cognitive outcome. Lean body mass associated with cognitive processing speed and bone mineral density associated with cognitive processing speed and verbal learning and memory. −Associations attenuated and nonsignificant after controlling for age and Expanded Disability Status Scale scores.

5 This article and any supplementary material should be cited as follows: Sandroff BM, Hubbard MS, Pilutti LA, Motl RW. No association between body composition and cognition in ambulatory persons with multiple sclerosis: A brief report. J Rehabil Res Dev. 2015;52(3):XX-XX. http://dx.doi.org/10.1682/JRRD.2014.09.0208 Slideshow Project DOI:10.1682/JRRD.2014.09.0208JSP Conclusion Body composition might not represent a target of interventions for improving cognitive processing speed or learning and memory in MS.

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