1. Toxicology Update Tracie Phillips, Ph.D. & Roberta Grant, Ph.D. Toxicology Division Texas Commission on Environmental Quality Environmental Trade Fair 2015

2. Objectives New Toxicology Database: Database Introduction Database Prototype Database Testing Updates to Odor Values: Odor Regulation Odor Changes Odor Timeline

3. T HE N EW T OXICOLOGY D ATABASE A new beginning NEW

4. What is the new database? Housed within the TAMIS database One stop shop: ESL List AMCV List Supporting documents

5. Why are we changing? Reduce errors Proper database structure More information/detail Dynamic Manual Spreadsheets 1000s of Chemicals Errors & Frustration

6. What will be different? 1. No more “Published List” spreadsheets

7. What will be different? 2. Information will be dynamic Database Updates New Info

8. What will be different? 3. ESL requests Consult the database 1 st No verification for existing values Database = Real Time At least a 2-week turnaround Each value documented Should be received early in the permitting process New ESL Request

9. What will be different? 4. All associated documentation will be linked: DSDs Fact sheets Public comments Interim documentation

10. What will be different? 5. Screening level reports Reports Toxicology Reports ESL Effects Screening Levels Summary Values Used in Permitting Only Detail All Values (Health & Welfare) AMCV Air Monitoring Comparison Values

11. What will be different? 6. More detail will be available: Each value will be dated

12. What will be different? 7. Source codes OdorInterim Long-termShort-term

13. What will be different? 8. List will be searchable by: Date Substance: CAS# Identified synonyms Substance type: Alcohols Surrogates

14. What will be different? 9. Use of surrogates: Promotes consistency Children Parent Chemical A Chemical X Chemical Z

15. What will be different? 10. Identified synonyms Styrene Phenyl- ethylene Vinyl benzene Styrene Monomer

16. What is the timeline? (4) Full Production – No More Published List: Date TBD (3) Transition & Beta Testing: Date TBD (2) External User Testing: Date TBD (1) Internal User Testing: Date TBD

17. P ROTOTYPE D EMO Time for a conceptual demonstration **For example purposes only, the following is not a true representation of the final product

18. TAMIS Welcome Screen

19. Login Screen

20. Report Selection Screen – Wizard Mode

21. Date Selection Screen

22. Report Parameter Criteria Screen

23. File Delimiter Selection Screen

24. Report Generation Screen

25. Report Output in Excel

26. T ESTING THE D ATABASE Testers Wanted!

27. External Testing If you would like to participate, send an e-mail to: Tracie Phillips: Tracie.Phillips@tceq.texas.govTracie.Phillips@tceq.texas.gov -or- Toxicology Division: tox@tceq.texas.govtox@tceq.texas.gov

28. P ROPOSED C HANGES TO THE D ERIVATION OF O DOR -B ASED V ALUES A needed change NEW

29. Why do we regulate odors? Odor is a leading cause of citizen complaints The Texas Clean Air Act Intent is regulation of odor to prevent nuisance conditions, not odor detection

30. Why are we changing? Derivation with the intention of preventing odor nuisance conditions Large differences in reported odor threshold values Consistency – all odor values derived at one time

31. What will be different? Available and reliable studies Historical data Study bias considerations Source Data Malodorous chemicals Generic/surrogation, if needed Chemical Classification Identify all potential values Data integration to determine final value Derivation

32. What is the timeline? Odor White Paper Toxicity Factor Guidelines Update Odor Values Finalized https://www.tceq.texas.gov/toxicology

33. Contact Information Roberta Grant, Ph.D. 512-239-4115 Roberta.Grant@tceq.texas.gov Tracie Phillips, Ph.D. 512-239-2269 Tracie.Phillips@tceq.texas.gov