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The Role of Chondrocyte Senescence in the Pathogenesis of Osteoarthritis and in Limiting Cartilage Repair by James A. Martin, and Joseph A. Buckwalter.

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Presentation on theme: "The Role of Chondrocyte Senescence in the Pathogenesis of Osteoarthritis and in Limiting Cartilage Repair by James A. Martin, and Joseph A. Buckwalter."— Presentation transcript:

1 The Role of Chondrocyte Senescence in the Pathogenesis of Osteoarthritis and in Limiting Cartilage Repair by James A. Martin, and Joseph A. Buckwalter J Bone Joint Surg Am Volume 85(suppl 2):106-110 April 1, 2003 ©2003 by The Journal of Bone and Joint Surgery, Inc.

2 Results of linear regression analysis of chondrocytes from donors of ranging in age from one to eighty-seven years. James A. Martin, and Joseph A. Buckwalter J Bone Joint Surg Am 2003;85:106-110 ©2003 by The Journal of Bone and Joint Surgery, Inc.

3 Ethidium bromide-stained agarose gel showing the products of long-distance polymerase chain reaction amplification of the mitochondrial genome at five, twelve, eighteen, and twenty-three population doublings. James A. Martin, and Joseph A. Buckwalter J Bone Joint Surg Am 2003;85:106-110 ©2003 by The Journal of Bone and Joint Surgery, Inc.

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