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N-Acetylcysteine Inhibits Post-Impact Chondrocyte Death in Osteochondral Explants by James A. Martin, Daniel McCabe, Morgan Walter, Joseph A. Buckwalter,

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Presentation on theme: "N-Acetylcysteine Inhibits Post-Impact Chondrocyte Death in Osteochondral Explants by James A. Martin, Daniel McCabe, Morgan Walter, Joseph A. Buckwalter,"— Presentation transcript:

1 N-Acetylcysteine Inhibits Post-Impact Chondrocyte Death in Osteochondral Explants by James A. Martin, Daniel McCabe, Morgan Walter, Joseph A. Buckwalter, and Todd O. McKinley J Bone Joint Surg Am Volume 91(8):1890-1897 August 1, 2009 ©2009 by The Journal of Bone and Joint Surgery, Inc.

2 Structural damage from impact injuries. James A. Martin et al. J Bone Joint Surg Am 2009;91:1890- 1897 ©2009 by The Journal of Bone and Joint Surgery, Inc.

3 Laser confocal imaging of viability stains. James A. Martin et al. J Bone Joint Surg Am 2009;91:1890- 1897 ©2009 by The Journal of Bone and Joint Surgery, Inc.

4 Time course of chondrocyte death after impact injury. James A. Martin et al. J Bone Joint Surg Am 2009;91:1890- 1897 ©2009 by The Journal of Bone and Joint Surgery, Inc.

5 Effects of drug treatment on post-impact chondrocyte viability. James A. Martin et al. J Bone Joint Surg Am 2009;91:1890- 1897 ©2009 by The Journal of Bone and Joint Surgery, Inc.

6 Effect of delaying N-acetylcysteine treatment. James A. Martin et al. J Bone Joint Surg Am 2009;91:1890- 1897 ©2009 by The Journal of Bone and Joint Surgery, Inc.

7 Effects of N-acetylcysteine on glycosaminoglycan (GAG) content seven and fourteen days after injury. James A. Martin et al. J Bone Joint Surg Am 2009;91:1890- 1897 ©2009 by The Journal of Bone and Joint Surgery, Inc.

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