1. 1D-NMR lesson 1 module 1 Acquisition and treatment of NMR data Prof. Claudio Santi Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

2. 1D-NMR Introduction Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia Mo represent a convenient way to describe a complete spin system. It is the vectorial sum of all the single vectors describing each single nuclear magnetic moment.

3. 1D-NMR Pulse NMR experimet Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia Pulse: Consist into applying a complete set of radio frequencies able to excite all the observed nuclei at the same time. Mo during the pulse, moves from the equilibrium (z axis) describing a spiral. After the pulse the system come back to the equilibrium giving rise the NMR signal

4. 1D-NMR The rotating frame Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

5. 1D-NMR Free Induction Decay Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

6. 1D-NMR FT-NMR treatment of the signal Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

7. 1D-NMR Acqisition and Treatment Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

8. 1D-NMR Acqisition and Treatment

9. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment

10. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment

11. 1D-NMR Acqisition and Treatment Digital Resolution Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

12. 1D-NMR Acqisition and Treatment (Shimming)

13. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment

14. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment

15. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment

16. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment

17. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment (RG)

18. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment (NS)

19. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment

20. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment (LB)

21. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment (LB-GB)

22. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment (Phase)

23. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment (Phase)

24. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Acqisition and Treatment (Phase Cycling)

25. 1D-NMR lesson 1 module 2 Decoupling techniques INEPT-DEPT powerful tools in 1D-NMR Prof. Claudio Santi Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

26. 1D-NMR Decoupling

27. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Homo Decoupling

28. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Hetero Decoupling

29. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR BB Decoupling

30. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Off Resonance Decoupling

31. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Polarization Transfer

32. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Polarization Transfer

33. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Polarization Transfer

34. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Decoupling (INEPT)

35. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Decoupling (refocused INEPT) refocusing

36. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Decoupling (refocused INEPT-BB) INEPT refocusing

37. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Decoupling & INEPT

38. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Comparing different experiments

39. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Comparing different experiments

40. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Decoupling (DEPT)

41. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Decoupling (DEPT)

42. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR Decoupling

43. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR 15 N INEPT

44. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR

45. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR

46. 1D-NMR Taxol Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

47. 1D-NMR Introduction Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

48. 1D-NMR additional

49. Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia 1D-NMR pulse angle

50. 1D-NMR additional quadrature detection Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia

51. 1D-NMR additional Prof. Claudio Santi Department of Chemistry and Technology of Drugs University of Perugia